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Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.
Suárez-Fariñas M, Ungar B, Noda S, Shroff A, Mansouri Y, Fuentes-Duculan J, Czernik A, Zheng X, Estrada YD, Xu H, Peng X, Shemer A, Krueger JG, Lebwohl MG, Guttman-Yassky E. Suárez-Fariñas M, et al. Among authors: mansouri y. J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24. J Allergy Clin Immunol. 2015. PMID: 26316095
Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism.
Guttman-Yassky E, Ungar B, Noda S, Suprun M, Shroff A, Dutt R, Khattri S, Min M, Mansouri Y, Zheng X, Estrada YD, Singer GK, Suarez-Farinas M, Krueger JG, Lebwohl MG. Guttman-Yassky E, et al. Among authors: mansouri y. J Allergy Clin Immunol. 2016 Jan;137(1):301-304. doi: 10.1016/j.jaci.2015.11.001. Epub 2015 Nov 20. J Allergy Clin Immunol. 2016. PMID: 26607705 No abstract available.
Phase 2 randomized, double-blind study of IL-17 targeting with secukinumab in atopic dermatitis.
Ungar B, Pavel AB, Li R, Kimmel G, Nia J, Hashim P, Kim HJ, Chima M, Vekaria AS, Estrada Y, Xu H, Peng X, Singer GK, Baum D, Mansouri Y, Taliercio M, Guttman-Yassky E. Ungar B, et al. Among authors: mansouri y. J Allergy Clin Immunol. 2021 Jan;147(1):394-397. doi: 10.1016/j.jaci.2020.04.055. Epub 2020 May 16. J Allergy Clin Immunol. 2021. PMID: 32428528 Clinical Trial. No abstract available.
A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata.
Mikhaylov D, Pavel A, Yao C, Kimmel G, Nia J, Hashim P, Vekaria AS, Taliercio M, Singer G, Karalekas R, Baum D, Mansouri Y, Lebwohl MG, Guttman-Yassky E. Mikhaylov D, et al. Among authors: mansouri y. Arch Dermatol Res. 2019 Jan;311(1):29-36. doi: 10.1007/s00403-018-1876-y. Epub 2018 Nov 11. Arch Dermatol Res. 2019. PMID: 30417279 Clinical Trial.
31 results