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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Rathert P, Roth M, Neumann T, Muerdter F, Roe JS, Muhar M, Deswal S, Cerny-Reiterer S, Peter B, Jude J, Hoffmann T, Boryń ŁM, Axelsson E, Schweifer N, Tontsch-Grunt U, Dow LE, Gianni D, Pearson M, Valent P, Stark A, Kraut N, Vakoc CR, Zuber J. Rathert P, et al. Among authors: deswal s. Nature. 2015 Sep 24;525(7570):543-547. doi: 10.1038/nature14898. Epub 2015 Sep 14. Nature. 2015. PMID: 26367798 Free PMC article.
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J. de Almeida M, et al. Among authors: deswal s. Nature. 2021 Nov;599(7885):491-496. doi: 10.1038/s41586-021-04035-8. Epub 2021 Oct 28. Nature. 2021. PMID: 34711951
BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
Hogg SJ, Vervoort SJ, Deswal S, Ott CJ, Li J, Cluse LA, Beavis PA, Darcy PK, Martin BP, Spencer A, Traunbauer AK, Sadovnik I, Bauer K, Valent P, Bradner JE, Zuber J, Shortt J, Johnstone RW. Hogg SJ, et al. Among authors: deswal s. Cell Rep. 2017 Feb 28;18(9):2162-2174. doi: 10.1016/j.celrep.2017.02.011. Cell Rep. 2017. PMID: 28249162 Free PMC article.
SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
Tordella L, Khan S, Hohmeyer A, Banito A, Klotz S, Raguz S, Martin N, Dhamarlingam G, Carroll T, González Meljem JM, Deswal S, Martínez-Barbera JP, García-Escudero R, Zuber J, Zender L, Gil J. Tordella L, et al. Among authors: deswal s. Genes Dev. 2016 Oct 1;30(19):2187-2198. doi: 10.1101/gad.286112.116. Epub 2016 Oct 13. Genes Dev. 2016. PMID: 27737960 Free PMC article.
Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM. Uribesalgo I, et al. Among authors: deswal s. EMBO Mol Med. 2019 Aug;11(8):e9266. doi: 10.15252/emmm.201809266. Epub 2019 Jun 24. EMBO Mol Med. 2019. PMID: 31267692 Free PMC article.
Pre-clustered TCR complexes.
Molnár E, Deswal S, Schamel WW. Molnár E, et al. Among authors: deswal s. FEBS Lett. 2010 Dec 15;584(24):4832-7. doi: 10.1016/j.febslet.2010.09.004. Epub 2010 Sep 7. FEBS Lett. 2010. PMID: 20828560 Free article. Review.
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