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A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP. Buchert M, et al. Among authors: ernst m. Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6. Dis Model Mech. 2015. PMID: 26398937 Free PMC article.
c-Myb is required for progenitor cell homeostasis in colonic crypts.
Malaterre J, Carpinelli M, Ernst M, Alexander W, Cooke M, Sutton S, Dworkin S, Heath JK, Frampton J, McArthur G, Clevers H, Hilton D, Mantamadiotis T, Ramsay RG. Malaterre J, et al. Among authors: ernst m. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3829-34. doi: 10.1073/pnas.0610055104. Epub 2007 Feb 26. Proc Natl Acad Sci U S A. 2007. PMID: 17360438 Free PMC article.
A33 antigen-deficient mice have defective colonic mucosal repair.
Pereira-Fantini PM, Judd LM, Kalantzis A, Peterson A, Ernst M, Heath JK, Giraud AS. Pereira-Fantini PM, et al. Among authors: ernst m. Inflamm Bowel Dis. 2010 Apr;16(4):604-12. doi: 10.1002/ibd.21114. Inflamm Bowel Dis. 2010. PMID: 19856415
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.
Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Näthke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M. Buchert M, et al. Among authors: ernst m. PLoS Genet. 2010 Jan 15;6(1):e1000816. doi: 10.1371/journal.pgen.1000816. PLoS Genet. 2010. PMID: 20084116 Free PMC article.
2,153 results