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399 results

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A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP. Buchert M, et al. Among authors: tan cw. Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6. Dis Model Mech. 2015. PMID: 26398937 Free PMC article.
Wnt signalling pathway parameters for mammalian cells.
Tan CW, Gardiner BS, Hirokawa Y, Layton MJ, Smith DW, Burgess AW. Tan CW, et al. PLoS One. 2012;7(2):e31882. doi: 10.1371/journal.pone.0031882. Epub 2012 Feb 21. PLoS One. 2012. PMID: 22363759 Free PMC article.
Colon cryptogenesis: asymmetric budding.
Tan CW, Hirokawa Y, Gardiner BS, Smith DW, Burgess AW. Tan CW, et al. PLoS One. 2013 Oct 21;8(10):e78519. doi: 10.1371/journal.pone.0078519. eCollection 2013. PLoS One. 2013. PMID: 24205248 Free PMC article.
Colonic myofibroblast cell line stimulates colonoid formation.
Hirokawa Y, Yip KH, Tan CW, Burgess AW. Hirokawa Y, et al. Among authors: tan cw. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G547-56. doi: 10.1152/ajpgi.00267.2013. Epub 2014 Jan 30. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24481605 Free article.
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Phesse TJ, Buchert M, Stuart E, Flanagan DJ, Faux M, Afshar-Sterle S, Walker F, Zhang HH, Nowell CJ, Jorissen R, Tan CW, Hirokawa Y, Eissmann MF, Poh AR, Malaterre J, Pearson HB, Kirsch DG, Provero P, Poli V, Ramsay RG, Sieber O, Burgess AW, Huszar D, Vincan E, Ernst M. Phesse TJ, et al. Among authors: tan cw. Sci Signal. 2014 Sep 30;7(345):ra92. doi: 10.1126/scisignal.2005411. Sci Signal. 2014. PMID: 25270258 Free article.
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL. Thilakasiri P, et al. Among authors: tan cw. EMBO Mol Med. 2019 Apr;11(4):e9539. doi: 10.15252/emmm.201809539. EMBO Mol Med. 2019. PMID: 30885958 Free PMC article.
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer.
Nguyen PM, Dagley LF, Preaudet A, Lam N, Giam M, Fung KY, Aizel K, van Duijneveldt G, Tan CW, Hirokawa Y, Yip HYK, Love CG, Poh AR, Cruz A, Burstroem C, Feltham R, Abdirahman SM, Meiselbach K, Low RRJ, Palmieri M, Ernst M, Webb AI, Burgess T, Sieber OM, Bouillet P, Putoczki TL. Nguyen PM, et al. Among authors: tan cw. Cell Death Differ. 2020 Feb;27(2):742-757. doi: 10.1038/s41418-019-0383-9. Epub 2019 Jul 11. Cell Death Differ. 2020. PMID: 31296963 Free PMC article.
399 results