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ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy.
Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT. Albright RA, et al. Among authors: braddock aa, braddock dt. Nat Commun. 2015 Dec 1;6:10006. doi: 10.1038/ncomms10006. Nat Commun. 2015. PMID: 26624227 Free PMC article.
NPP4 is a procoagulant enzyme on the surface of vascular endothelium.
Albright RA, Chang WC, Robert D, Ornstein DL, Cao W, Liu L, Redick ME, Young JI, De La Cruz EM, Braddock DT. Albright RA, et al. Among authors: braddock dt. Blood. 2012 Nov 22;120(22):4432-40. doi: 10.1182/blood-2012-04-425215. Epub 2012 Sep 20. Blood. 2012. PMID: 22995898 Free PMC article.
Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency.
Oheim R, Zimmerman K, Maulding ND, Stürznickel J, von Kroge S, Kavanagh D, Stabach PR, Kornak U, Tommasini SM, Horowitz MC, Amling M, Thompson D, Schinke T, Busse B, Carpenter TO, Braddock DT. Oheim R, et al. Among authors: braddock dt. J Bone Miner Res. 2020 Mar;35(3):528-539. doi: 10.1002/jbmr.3911. Epub 2019 Dec 5. J Bone Miner Res. 2020. PMID: 31805212 Free PMC article.
Clinical and Biochemical Phenotypes in a Family With ENPP1 Mutations.
Kotwal A, Ferrer A, Kumar R, Singh RJ, Murthy V, Schultz-Rogers L, Zimmermann M, Lanpher B, Zimmerman K, Stabach PR, Klee E, Braddock DT, Wermers RA. Kotwal A, et al. Among authors: braddock dt. J Bone Miner Res. 2020 Apr;35(4):662-670. doi: 10.1002/jbmr.3938. Epub 2020 Jan 16. J Bone Miner Res. 2020. PMID: 31826312 Free PMC article.
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass.
Zimmerman K, Liu X, von Kroge S, Stabach P, Lester ER, Chu EY, Srivastava S, Somerman MJ, Tommasini SM, Busse B, Schinke T, Carpenter TO, Oheim R, Braddock DT. Zimmerman K, et al. Among authors: braddock dt. J Bone Miner Res. 2022 Sep;37(9):1733-1749. doi: 10.1002/jbmr.4640. Epub 2022 Jul 29. J Bone Miner Res. 2022. PMID: 35773783 Free PMC article.
Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice.
Ferreira CR, Kavanagh D, Oheim R, Zimmerman K, Stürznickel J, Li X, Stabach P, Rettig RL, Calderone L, MacKichan C, Wang A, Hutchinson HA, Nelson T, Tommasini SM, von Kroge S, Fiedler IA, Lester ER, Moeckel GW, Busse B, Schinke T, Carpenter TO, Levine MA, Horowitz MC, Braddock DT. Ferreira CR, et al. Among authors: braddock dt. J Bone Miner Res. 2021 May;36(5):942-955. doi: 10.1002/jbmr.4254. Epub 2021 Feb 18. J Bone Miner Res. 2021. PMID: 33465815 Free PMC article.
48 results