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Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses.
Ruane D, Chorny A, Lee H, Faith J, Pandey G, Shan M, Simchoni N, Rahman A, Garg A, Weinstein EG, Oropallo M, Gaylord M, Ungaro R, Cunningham-Rundles C, Alexandropoulos K, Mucida D, Merad M, Cerutti A, Mehandru S. Ruane D, et al. J Exp Med. 2016 Jan 11;213(1):53-73. doi: 10.1084/jem.20150567. Epub 2015 Dec 28. J Exp Med. 2016. PMID: 26712806 Free PMC article.
Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils.
Chen K, Xu W, Wilson M, He B, Miller NW, Bengtén E, Edholm ES, Santini PA, Rath P, Chiu A, Cattalini M, Litzman J, B Bussel J, Huang B, Meini A, Riesbeck K, Cunningham-Rundles C, Plebani A, Cerutti A. Chen K, et al. Nat Immunol. 2009 Aug;10(8):889-98. doi: 10.1038/ni.1748. Epub 2009 Jun 28. Nat Immunol. 2009. PMID: 19561614 Free PMC article.
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, Shan M, Xiong H, Bussel JB, Chiu A, Puel A, Reichenbach J, Marodi L, Döffinger R, Vasconcelos J, Issekutz A, Krause J, Davies G, Li X, Grimbacher B, Plebani A, Meffre E, Picard C, Cunningham-Rundles C, Casanova JL, Cerutti A. He B, et al. Nat Immunol. 2010 Sep;11(9):836-45. doi: 10.1038/ni.1914. Epub 2010 Aug 1. Nat Immunol. 2010. PMID: 20676093 Free PMC article.
B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.
Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, Comerma L, Chorny A, Shan M, Xu W, Magri G, Knowles DM, Tam W, Chiu A, Bussel JB, Serrano S, Lorente JA, Bellosillo B, Lloreta J, Juanpere N, Alameda F, Baró T, de Heredia CD, Torán N, Català A, Torrebadell M, Fortuny C, Cusí V, Carreras C, Diaz GA, Blander JM, Farber CM, Silvestri G, Cunningham-Rundles C, Calvillo M, Dufour C, Notarangelo LD, Lougaris V, Plebani A, Casanova JL, Ganal SC, Diefenbach A, Aróstegui JI, Juan M, Yagüe J, Mahlaoui N, Donadieu J, Chen K, Cerutti A. Puga I, et al. Nat Immunol. 2011 Dec 25;13(2):170-80. doi: 10.1038/ni.2194. Nat Immunol. 2011. PMID: 22197976 Free PMC article.
Differential induction of plasma cells by isoforms of human TACI.
Garcia-Carmona Y, Cols M, Ting AT, Radigan L, Yuk FJ, Zhang L, Cerutti A, Cunningham-Rundles C. Garcia-Carmona Y, et al. Blood. 2015 Mar 12;125(11):1749-58. doi: 10.1182/blood-2014-05-575845. Epub 2015 Jan 28. Blood. 2015. PMID: 25631768 Free PMC article.
399 results