Roland BP - Search Results

1

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.

Roland BP, Zeccola AM, Larsen SB, Amrich CG, Talsma AD, Stuchul KA, Heroux A, Levitan ES, VanDemark AP, Palladino MJ. Roland BP, et al. PLoS Genet. 2016 Mar 31;12(3):e1005941. doi: 10.1371/journal.pgen.1005941. eCollection 2016 Mar. PLoS Genet. 2016. PMID: 27031109 Free PMC article.

2

Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity.

Roland BP, Stuchul KA, Larsen SB, Amrich CG, Vandemark AP, Celotto AM, Palladino MJ. Roland BP, et al. J Cell Sci. 2013 Jul 15;126(Pt 14):3151-8. doi: 10.1242/jcs.124586. Epub 2013 May 2. J Cell Sci. 2013. PMID: 23641070 Free PMC article.

3

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.

Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ. Roland BP, et al. Biochim Biophys Acta. 2015 Jan;1852(1):61-9. doi: 10.1016/j.bbadis.2014.10.010. Epub 2014 Oct 16. Biochim Biophys Acta. 2015. PMID: 25463631 Free PMC article.

4

Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.

Roland BP, Richards KR, Hrizo SL, Eicher S, Barile ZJ, Chang TC, Savon G, Bianchi P, Fermo E, Ricerca BM, Tortorolo L, Vockley J, VanDemark AP, Palladino MJ. Roland BP, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2257-2266. doi: 10.1016/j.bbadis.2019.05.002. Epub 2019 May 7. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31075491 Free PMC article.

5

Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo.

Taverner AM, Yang L, Barile ZJ, Lin B, Peng J, Pinharanda AP, Rao AS, Roland BP, Talsma AD, Wei D, Petschenka G, Palladino MJ, Andolfatto P. Taverner AM, et al. Among authors: roland bp. Elife. 2019 Aug 27;8:e48224. doi: 10.7554/eLife.48224. Elife. 2019. PMID: 31453806 Free PMC article.

6

Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies.

Yang L, Borne F, Betz A, Aardema ML, Zhen Y, Peng J, Visconti R, Wu M, Roland BP, Talsma AD, Palladino MJ, Petschenka G, Andolfatto P. Yang L, et al. Among authors: roland bp. Curr Biol. 2023 Dec 4;33(23):5160-5168.e7. doi: 10.1016/j.cub.2023.10.063. Epub 2023 Nov 20. Curr Biol. 2023. PMID: 37989309

7

Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.

Mishra R, Jayaraman M, Roland BP, Landrum E, Fullam T, Kodali R, Thakur AK, Arduini I, Wetzel R. Mishra R, et al. Among authors: roland bp. J Mol Biol. 2012 Feb 3;415(5):900-17. doi: 10.1016/j.jmb.2011.12.011. Epub 2011 Dec 9. J Mol Biol. 2012. PMID: 22178478 Free PMC article.

8

A serendipitous survey of prediction algorithms for amyloidogenicity.

Roland BP, Kodali R, Mishra R, Wetzel R. Roland BP, et al. Biopolymers. 2013 Nov;100(6):780-9. doi: 10.1002/bip.22305. Biopolymers. 2013. PMID: 23893755 Free PMC article.

9

Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase.

Roland BP, Graham TR. Roland BP, et al. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4460-6. doi: 10.1073/pnas.1525730113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432949 Free PMC article.

10

Decoding P4-ATPase substrate interactions.

Roland BP, Graham TR. Roland BP, et al. Crit Rev Biochem Mol Biol. 2016 Nov/Dec;51(6):513-527. doi: 10.1080/10409238.2016.1237934. Epub 2016 Oct 4. Crit Rev Biochem Mol Biol. 2016. PMID: 27696908 Free PMC article. Review.

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