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The TBK1-binding domain of optineurin promotes type I interferon responses.
Meena NP, Zhu G, Mittelstadt PR, Giardino Torchia ML, Pourcelot M, Arnoult D, Ashwell JD, Munitic I. Meena NP, et al. Among authors: giardino torchia ml. FEBS Lett. 2016 May;590(10):1498-508. doi: 10.1002/1873-3468.12176. Epub 2016 May 4. FEBS Lett. 2016. PMID: 27086836 Free PMC article.
Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome.
Giardino Torchia ML, Dutta D, Mittelstadt PR, Guha J, Gaida MM, Fish K, Barr VA, Akpan IO, Samelson LE, Tagad HD, Debnath S, Miller Jenkins LM, Appella E, Ashwell JD. Giardino Torchia ML, et al. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2174-2179. doi: 10.1073/pnas.1713301115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440413 Free PMC article.
c-IAP1 and c-IAP2 redundancy differs between T and B cells.
Giardino Torchia ML, Conze DB, Ashwell JD. Giardino Torchia ML, et al. PLoS One. 2013 Jun 17;8(6):e66161. doi: 10.1371/journal.pone.0066161. Print 2013. PLoS One. 2013. PMID: 23799077 Free PMC article.
CD70 is downregulated by interaction with CD27.
Kuka M, Munitic I, Giardino Torchia ML, Ashwell JD. Kuka M, et al. Among authors: giardino torchia ml. J Immunol. 2013 Sep 1;191(5):2282-9. doi: 10.4049/jimmunol.1300868. Epub 2013 Aug 2. J Immunol. 2013. PMID: 23913967 Free PMC article.
Getting MAD at MYC.
Giardino Torchia ML, Ashwell JD. Giardino Torchia ML, et al. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):9821-9823. doi: 10.1073/pnas.1813867115. Epub 2018 Sep 10. Proc Natl Acad Sci U S A. 2018. PMID: 30201726 Free PMC article. No abstract available.
16 results