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Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.
Wälti MA, Ravotti F, Arai H, Glabe CG, Wall JS, Böckmann A, Güntert P, Meier BH, Riek R. Wälti MA, et al. Among authors: glabe cg. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4976-84. doi: 10.1073/pnas.1600749113. Epub 2016 Jul 28. Proc Natl Acad Sci U S A. 2016. PMID: 27469165 Free PMC article.
Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques.
Pensalfini A, Albay R 3rd, Rasool S, Wu JW, Hatami A, Arai H, Margol L, Milton S, Poon WW, Corrada MM, Kawas CH, Glabe CG. Pensalfini A, et al. Among authors: glabe cg. Neurobiol Dis. 2014 Nov;71:53-61. doi: 10.1016/j.nbd.2014.07.011. Epub 2014 Aug 1. Neurobiol Dis. 2014. PMID: 25092575 Free PMC article.
Structural differences between amyloid beta oligomers.
Breydo L, Kurouski D, Rasool S, Milton S, Wu JW, Uversky VN, Lednev IK, Glabe CG. Breydo L, et al. Among authors: glabe cg. Biochem Biophys Res Commun. 2016 Sep 2;477(4):700-705. doi: 10.1016/j.bbrc.2016.06.122. Epub 2016 Jun 27. Biochem Biophys Res Commun. 2016. PMID: 27363332
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates.
Liu C, Zhao M, Jiang L, Cheng PN, Park J, Sawaya MR, Pensalfini A, Gou D, Berk AJ, Glabe CG, Nowick J, Eisenberg D. Liu C, et al. Among authors: glabe cg. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20913-8. doi: 10.1073/pnas.1218792109. Epub 2012 Dec 3. Proc Natl Acad Sci U S A. 2012. PMID: 23213214 Free PMC article.
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors.
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. Krotee P, et al. Among authors: glabe cg. J Biol Chem. 2018 Feb 23;293(8):2888-2902. doi: 10.1074/jbc.M117.806109. Epub 2017 Dec 27. J Biol Chem. 2018. PMID: 29282295 Free PMC article.
157 results