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Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.
Nakagawa S, Wei L, Song WM, Higashi T, Ghoshal S, Kim RS, Bian CB, Yamada S, Sun X, Venkatesh A, Goossens N, Bain G, Lauwers GY, Koh AP, El-Abtah M, Ahmad NB, Hoshida H, Erstad DJ, Gunasekaran G, Lee Y, Yu ML, Chuang WL, Dai CY, Kobayashi M, Kumada H, Beppu T, Baba H, Mahajan M, Nair VD, Lanuti M, Villanueva A, Sangiovanni A, Iavarone M, Colombo M, Llovet JM, Subramanian A, Tager AM, Friedman SL, Baumert TF, Schwarz ME, Chung RT, Tanabe KK, Zhang B, Fuchs BC, Hoshida Y; Precision Liver Cancer Prevention Consortium. Nakagawa S, et al. Cancer Cell. 2016 Dec 12;30(6):879-890. doi: 10.1016/j.ccell.2016.11.004. Cancer Cell. 2016. PMID: 27960085 Free PMC article.
Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.
Deshmukh M, Nakagawa S, Higashi T, Vincek A, Venkatesh A, Ruiz de Galarreta M, Koh AP, Goossens N, Hirschfield H, Bian CB, Fujiwara N, Ono A, Hoshida H, El-Abtah M, Ahmad NB, Lujambio A, Sanchez R, Fuchs BC, Poelstra K, Prakash J, Hoshida Y; Precision Liver Cancer Prevention Consortium. Deshmukh M, et al. Among authors: nakagawa s. Nanomedicine. 2018 Feb;14(2):317-325. doi: 10.1016/j.nano.2017.11.004. Epub 2017 Nov 20. Nanomedicine. 2018. PMID: 29157977 Free PMC article.
Molecular prognostic prediction in liver cirrhosis.
Goossens N, Nakagawa S, Hoshida Y. Goossens N, et al. Among authors: nakagawa s. World J Gastroenterol. 2015 Sep 28;21(36):10262-73. doi: 10.3748/wjg.v21.i36.10262. World J Gastroenterol. 2015. PMID: 26420954 Free PMC article. Review.
Novel substituted aminothiazoles as potent and selective anti-hepatocellular carcinoma agents.
Lu H, Rogowskyj J, Yu W, Venkatesh A, Khan N, Nakagawa S, Goossens N, Koh AP, Higashi T, Gunasekaran G, Schwarz ME, Hiotis SP, Xu X, Kinney W, Hoshida Y, Block T, Cuconati A, Du Y. Lu H, et al. Among authors: nakagawa s. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5819-5824. doi: 10.1016/j.bmcl.2016.10.015. Epub 2016 Oct 10. Bioorg Med Chem Lett. 2016. PMID: 27793566 Free PMC article.
Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.
Bollard J, Miguela V, Ruiz de Galarreta M, Venkatesh A, Bian CB, Roberto MP, Tovar V, Sia D, Molina-Sánchez P, Nguyen CB, Nakagawa S, Llovet JM, Hoshida Y, Lujambio A. Bollard J, et al. Among authors: nakagawa s. Gut. 2017 Jul;66(7):1286-1296. doi: 10.1136/gutjnl-2016-312268. Epub 2016 Nov 14. Gut. 2017. PMID: 27849562 Free PMC article.
Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases.
Bansal R, Nakagawa S, Yazdani S, van Baarlen J, Venkatesh A, Koh AP, Song WM, Goossens N, Watanabe H, Beasley MB, Powell CA, Storm G, Kaminski N, van Goor H, Friedman SL, Hoshida Y, Prakash J. Bansal R, et al. Among authors: nakagawa s. Exp Mol Med. 2017 Nov 17;49(11):e396. doi: 10.1038/emm.2017.213. Exp Mol Med. 2017. PMID: 29147013 Free PMC article.
Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease.
Fujiwara N, Kubota N, Crouchet E, Koneru B, Marquez CA, Jajoriya AK, Panda G, Qian T, Zhu S, Goossens N, Wang X, Liang S, Zhong Z, Lewis S, Taouli B, Schwartz ME, Fiel MI, Singal AG, Marrero JA, Fobar AJ, Parikh ND, Raman I, Li QZ, Taguri M, Ono A, Aikata H, Nakahara T, Nakagawa H, Matsushita Y, Tateishi R, Koike K, Kobayashi M, Higashi T, Nakagawa S, Yamashita YI, Beppu T, Baba H, Kumada H, Chayama K, Baumert TF, Hoshida Y. Fujiwara N, et al. Among authors: nakagawa s, nakagawa h. Sci Transl Med. 2022 Jun 22;14(650):eabo4474. doi: 10.1126/scitranslmed.abo4474. Epub 2022 Jun 22. Sci Transl Med. 2022. PMID: 35731891 Free PMC article.
Steatohepatitic Variant of Hepatocellular Carcinoma Is Associated With Both Alcoholic Steatohepatitis and Nonalcoholic Steatohepatitis: A Study of 2 Cohorts With Molecular Insights.
Qin J, Higashi T, Nakagawa S, Fujiwara N, Yamashita YI, Beppu T, Baba H, Kobayashi M, Kumada H, Gunasekaran G, Schiano TD, Thung SN, Fiel MI, Hoshida Y, Ward SC. Qin J, et al. Among authors: nakagawa s. Am J Surg Pathol. 2020 Oct;44(10):1406-1412. doi: 10.1097/PAS.0000000000001533. Am J Surg Pathol. 2020. PMID: 32618599 Free PMC article.
3,716 results