Kvaratskhelia M - Search Results

1

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.

Passos DO, Li M, Yang R, Rebensburg SV, Ghirlando R, Jeon Y, Shkriabai N, Kvaratskhelia M, Craigie R, Lyumkis D. Passos DO, et al. Among authors: kvaratskhelia m. Science. 2017 Jan 6;355(6320):89-92. doi: 10.1126/science.aah5163. Science. 2017. PMID: 28059769 Free PMC article.

2

Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry.

Shkriabai N, Patil SS, Hess S, Budihas SR, Craigie R, Burke TR Jr, Le Grice SF, Kvaratskhelia M. Shkriabai N, et al. Among authors: kvaratskhelia m. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6894-9. doi: 10.1073/pnas.0400873101. Epub 2004 Apr 26. Proc Natl Acad Sci U S A. 2004. PMID: 15118107 Free PMC article.

3

Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor.

Williams KL, Zhang Y, Shkriabai N, Karki RG, Nicklaus MC, Kotrikadze N, Hess S, Le Grice SF, Craigie R, Pathak VK, Kvaratskhelia M. Williams KL, et al. Among authors: kvaratskhelia m. J Biol Chem. 2005 Mar 4;280(9):7949-55. doi: 10.1074/jbc.M413579200. Epub 2004 Dec 22. J Biol Chem. 2005. PMID: 15615720 Free article.

4

Structural basis for dimerization of LAP2alpha, a component of the nuclear lamina.

Bradley CM, Jones S, Huang Y, Suzuki Y, Kvaratskhelia M, Hickman AB, Craigie R, Dyda F. Bradley CM, et al. Among authors: kvaratskhelia m. Structure. 2007 Jun;15(6):643-53. doi: 10.1016/j.str.2007.04.007. Structure. 2007. PMID: 17562312 Free article.

5

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding.

Zhao Z, McKee CJ, Kessl JJ, Santos WL, Daigle JE, Engelman A, Verdine G, Kvaratskhelia M. Zhao Z, et al. Among authors: kvaratskhelia m. J Biol Chem. 2008 Feb 29;283(9):5632-41. doi: 10.1074/jbc.M705241200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093980 Free PMC article.

6

FRET analysis reveals distinct conformations of IN tetramers in the presence of viral DNA or LEDGF/p75.

Kessl JJ, Li M, Ignatov M, Shkriabai N, Eidahl JO, Feng L, Musier-Forsyth K, Craigie R, Kvaratskhelia M. Kessl JJ, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2011 Nov 1;39(20):9009-22. doi: 10.1093/nar/gkr581. Epub 2011 Jul 19. Nucleic Acids Res. 2011. PMID: 21771857 Free PMC article.

7

Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.

Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M. Kessl JJ, et al. Among authors: kvaratskhelia m. J Biol Chem. 2012 May 11;287(20):16801-11. doi: 10.1074/jbc.M112.354373. Epub 2012 Mar 21. J Biol Chem. 2012. PMID: 22437836 Free PMC article.

8

Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2).

Larue R, Gupta K, Wuensch C, Shkriabai N, Kessl JJ, Danhart E, Feng L, Taltynov O, Christ F, Van Duyne GD, Debyser Z, Foster MP, Kvaratskhelia M. Larue R, et al. Among authors: kvaratskhelia m. J Biol Chem. 2012 Oct 5;287(41):34044-58. doi: 10.1074/jbc.M112.384669. Epub 2012 Aug 7. J Biol Chem. 2012. PMID: 22872640 Free PMC article.

9

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.

Eidahl JO, Crowe BL, North JA, McKee CJ, Shkriabai N, Feng L, Plumb M, Graham RL, Gorelick RJ, Hess S, Poirier MG, Foster MP, Kvaratskhelia M. Eidahl JO, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2013 Apr 1;41(6):3924-36. doi: 10.1093/nar/gkt074. Epub 2013 Feb 8. Nucleic Acids Res. 2013. PMID: 23396443 Free PMC article.

10

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes.

Larue RC, Plumb MR, Crowe BL, Shkriabai N, Sharma A, DiFiore J, Malani N, Aiyer SS, Roth MJ, Bushman FD, Foster MP, Kvaratskhelia M. Larue RC, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2014 Apr;42(8):4868-81. doi: 10.1093/nar/gku135. Epub 2014 Feb 11. Nucleic Acids Res. 2014. PMID: 24520112 Free PMC article.

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