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Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.
Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP. Cerqueira GC, et al. Among authors: cosimi la. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1135-1140. doi: 10.1073/pnas.1616248114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096418 Free PMC article.
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.
Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT. Barczak AK, et al. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6217-22. doi: 10.1073/pnas.1119540109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474362 Free PMC article.
Staphylococcal enterotoxin P predicts bacteremia in hospitalized patients colonized with methicillin-resistant Staphylococcus aureus.
Calderwood MS, Desjardins CA, Sakoulas G, Nicol R, Dubois A, Delaney ML, Kleinman K, Cosimi LA, Feldgarden M, Onderdonk AB, Birren BW, Platt R, Huang SS; CDC Prevention Epicenters Program. Calderwood MS, et al. Among authors: cosimi la. J Infect Dis. 2014 Feb 15;209(4):571-7. doi: 10.1093/infdis/jit501. Epub 2013 Sep 16. J Infect Dis. 2014. PMID: 24041793 Free PMC article.
Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination.
Bhattacharyya RP, Bandyopadhyay N, Ma P, Son SS, Liu J, He LL, Wu L, Khafizov R, Boykin R, Cerqueira GC, Pironti A, Rudy RF, Patel MM, Yang R, Skerry J, Nazarian E, Musser KA, Taylor J, Pierce VM, Earl AM, Cosimi LA, Shoresh N, Beechem J, Livny J, Hung DT. Bhattacharyya RP, et al. Among authors: cosimi la. Nat Med. 2019 Dec;25(12):1858-1864. doi: 10.1038/s41591-019-0650-9. Epub 2019 Nov 25. Nat Med. 2019. PMID: 31768064 Free PMC article.
Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance.
Salamzade R, Manson AL, Walker BJ, Brennan-Krohn T, Worby CJ, Ma P, He LL, Shea TP, Qu J, Chapman SB, Howe W, Young SK, Wurster JI, Delaney ML, Kanjilal S, Onderdonk AB, Bittencourt CE, Gussin GM, Kim D, Peterson EM, Ferraro MJ, Hooper DC, Shenoy ES, Cuomo CA, Cosimi LA, Huang SS, Kirby JE, Pierce VM, Bhattacharyya RP, Earl AM. Salamzade R, et al. Among authors: cosimi la. Genome Med. 2022 Apr 5;14(1):37. doi: 10.1186/s13073-022-01040-y. Genome Med. 2022. PMID: 35379360 Free PMC article.
Feasibility and lessons learned on remote trial implementation from TestBoston, a fully remote, longitudinal, large-scale COVID-19 surveillance study.
Naz-McLean S, Kim A, Zimmer A, Laibinis H, Lapan J, Tyman P, Hung J, Kelly C, Nagireddy H, Narayanan-Pandit S, McCarthy M, Ratnaparkhi S, Rutherford H, Patel R, Dryden-Peterson S, Hung DT, Woolley AE, Cosimi LA. Naz-McLean S, et al. Among authors: cosimi la. PLoS One. 2022 Jun 3;17(6):e0269127. doi: 10.1371/journal.pone.0269127. eCollection 2022. PLoS One. 2022. PMID: 35657813 Free PMC article.
31 results