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Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.
Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP. Cerqueira GC, et al. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1135-1140. doi: 10.1073/pnas.1616248114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096418 Free PMC article.
Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU.
Reis-Cunha JL, Baptista RP, Rodrigues-Luiz GF, Coqueiro-Dos-Santos A, Valdivia HO, de Almeida LV, Cardoso MS, D'Ávila DA, Dias FHC, Fujiwara RT, Galvão LMC, Chiari E, Cerqueira GC, Bartholomeu DC. Reis-Cunha JL, et al. BMC Genomics. 2018 Nov 13;19(1):816. doi: 10.1186/s12864-018-5198-4. BMC Genomics. 2018. PMID: 30424726 Free PMC article.
Accessing the Variability of Multicopy Genes in Complex Genomes using Unassembled Next-Generation Sequencing Reads: The Case of Trypanosoma cruzi Multigene Families.
Reis-Cunha JL, Coqueiro-Dos-Santos A, Pimenta-Carvalho SA, Marques LP, Rodrigues-Luiz GF, Baptista RP, Almeida LV, Honorato NRM, Lobo FP, Fraga VG, Galvão LMDC, Bueno LL, Fujiwara RT, Cardoso MS, Cerqueira GC, Bartholomeu DC. Reis-Cunha JL, et al. mBio. 2022 Dec 20;13(6):e0231922. doi: 10.1128/mbio.02319-22. Epub 2022 Oct 20. mBio. 2022. PMID: 36264102 Free PMC article.
Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi.
Talavera-López C, Messenger LA, Lewis MD, Yeo M, Reis-Cunha JL, Matos GM, Bartholomeu DC, Calzada JE, Saldaña A, Ramírez JD, Guhl F, Ocaña-Mayorga S, Costales JA, Gorchakov R, Jones K, Nolan MS, Teixeira SMR, Carrasco HJ, Bottazzi ME, Hotez PJ, Murray KO, Grijalva MJ, Burleigh B, Grisard EC, Miles MA, Andersson B. Talavera-López C, et al. Front Cell Infect Microbiol. 2021 Mar 3;11:614665. doi: 10.3389/fcimb.2021.614665. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 33747978 Free PMC article.
Identification of strain-specific B-cell epitopes in Trypanosoma cruzi using genome-scale epitope prediction and high-throughput immunoscreening with peptide arrays.
Mendes TA, Reis Cunha JL, de Almeida Lourdes R, Rodrigues Luiz GF, Lemos LD, dos Santos AR, da Câmara AC, Galvão LM, Bern C, Gilman RH, Fujiwara RT, Gazzinelli RT, Bartholomeu DC. Mendes TA, et al. PLoS Negl Trop Dis. 2013 Oct 31;7(10):e2524. doi: 10.1371/journal.pntd.0002524. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24205430 Free PMC article.
49 results