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A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Southwell AL, Skotte NH, Villanueva EB, Østergaard ME, Gu X, Kordasiewicz HB, Kay C, Cheung D, Xie Y, Waltl S, Dal Cengio L, Findlay-Black H, Doty CN, Petoukhov E, Iworima D, Slama R, Ooi J, Pouladi MA, Yang XW, Swayze EE, Seth PP, Hayden MR. Southwell AL, et al. Among authors: slama r. Hum Mol Genet. 2017 Mar 15;26(6):1115-1132. doi: 10.1093/hmg/ddx021. Hum Mol Genet. 2017. PMID: 28104789
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.
Southwell AL, Smith-Dijak A, Kay C, Sepers M, Villanueva EB, Parsons MP, Xie Y, Anderson L, Felczak B, Waltl S, Ko S, Cheung D, Dal Cengio L, Slama R, Petoukhov E, Raymond LA, Hayden MR. Southwell AL, et al. Among authors: slama r. Hum Mol Genet. 2016 Sep 1;25(17):3654-3675. doi: 10.1093/hmg/ddw212. Epub 2016 Jul 4. Hum Mol Genet. 2016. PMID: 27378694 Free PMC article.
Epigenetic footprints: Investigating placental DNA methylation in the context of prenatal exposure to phenols and phthalates.
Jedynak P, Siroux V, Broséus L, Tost J, Busato F, Gabet S, Thomsen C, Sakhi AK, Sabaredzovic A, Lyon-Caen S, Bayat S, Slama R, Philippat C, Lepeule J. Jedynak P, et al. Among authors: slama r. Environ Int. 2024 May 28;189:108763. doi: 10.1016/j.envint.2024.108763. Online ahead of print. Environ Int. 2024. PMID: 38824843 Free article.
Machine learning-based health environmental-clinical risk scores in European children.
Guimbaud JB, Siskos AP, Sakhi AK, Heude B, Sabidó E, Borràs E, Keun H, Wright J, Julvez J, Urquiza J, Gützkow KB, Chatzi L, Casas M, Bustamante M, Nieuwenhuijsen M, Vrijheid M, López-Vicente M, de Castro Pascual M, Stratakis N, Robinson O, Grazuleviciene R, Slama R, Alemany S, Basagaña X, Plantevit M, Cazabet R, Maitre L. Guimbaud JB, et al. Among authors: slama r. Commun Med (Lond). 2024 May 23;4(1):98. doi: 10.1038/s43856-024-00513-y. Commun Med (Lond). 2024. PMID: 38783062 Free PMC article.
Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children.
Güil-Oumrait N, Stratakis N, Maitre L, Anguita-Ruiz A, Urquiza J, Fabbri L, Basagaña X, Heude B, Haug LS, Sakhi AK, Iszatt N, Keun HC, Wright J, Chatzi L, Vafeiadi M, Bustamante M, Grazuleviciene R, Andrušaityte S, Slama R, McEachan R, Casas M, Vrijheid M. Güil-Oumrait N, et al. Among authors: slama r. JAMA Netw Open. 2024 May 1;7(5):e2412040. doi: 10.1001/jamanetworkopen.2024.12040. JAMA Netw Open. 2024. PMID: 38780942 Free PMC article.
Fetal and Infancy Exposure to Phenols, Parabens, and Phthalates and Anthropometric Measurements up to 36 Months, in the Longitudinal SEPAGES Cohort.
Ouidir M, Cissé AH, Botton J, Lyon-Caen S, Thomsen C, Sakhi AK, Sabaredzovic A, Bayat S, Slama R, Heude B, Philippat C. Ouidir M, et al. Among authors: slama r. Environ Health Perspect. 2024 May;132(5):57002. doi: 10.1289/EHP13644. Epub 2024 May 10. Environ Health Perspect. 2024. PMID: 38728218 Free PMC article.
Placental DNA methylation signatures of prenatal air pollution exposure and potential effects on birth outcomes: an analysis of three prospective cohorts.
Broséus L, Guilbert A, Hough I, Kloog I, Chauvaud A, Seyve E, Vaiman D, Heude B, Chevrier C, Tost J, Slama R, Lepeule J. Broséus L, et al. Among authors: slama r. Lancet Planet Health. 2024 May;8(5):e297-e308. doi: 10.1016/S2542-5196(24)00045-7. Epub 2024 May 6. Lancet Planet Health. 2024. PMID: 38723642 Free article.
709 results