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A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5.
Tilton JC, Wilen CB, Didigu CA, Sinha R, Harrison JE, Agrawal-Gamse C, Henning EA, Bushman FD, Martin JN, Deeks SG, Doms RW. Tilton JC, et al. Among authors: bushman fd. J Virol. 2010 Oct;84(20):10863-76. doi: 10.1128/JVI.01109-10. Epub 2010 Aug 11. J Virol. 2010. PMID: 20702642 Free PMC article.
Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
Morris EC, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, Grace S, Gilmour K, Workman S, Buckland K, Butler K, Chee R, Salama AD, Ibrahim H, Hara H, Duret C, Mavilio F, Male F, Bushman FD, Galy A, Burns SO, Gaspar HB, Thrasher AJ. Morris EC, et al. Among authors: bushman fd. Blood. 2017 Sep 14;130(11):1327-1335. doi: 10.1182/blood-2017-04-777136. Epub 2017 Jul 17. Blood. 2017. PMID: 28716862 Free PMC article.
Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicating.
Tanneti NS, Patel AK, Tan LH, Marques AD, Perera RAPM, Sherrill-Mix S, Kelly BJ, Renner DM, Collman RG, Rodino K, Lee C, Bushman FD, Cohen NA, Weiss SR. Tanneti NS, et al. Among authors: bushman fd. mBio. 2024 Apr 10;15(4):e0312923. doi: 10.1128/mbio.03129-23. Epub 2024 Mar 13. mBio. 2024. PMID: 38477472 Free PMC article.
Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a.
Armani-Tourret M, Gao C, Hartana CA, Sun W, Carrere L, Vela L, Hochroth A, Bellefroid M, Sbrolla A, Shea K, Flynn T, Roseto I, Rassadkina Y, Lee C, Giguel F, Malhotra R, Bushman FD, Gandhi RT, Yu XG, Kuritzkes DR, Lichterfeld M. Armani-Tourret M, et al. Among authors: bushman fd. Cell. 2024 Feb 29;187(5):1238-1254.e14. doi: 10.1016/j.cell.2024.01.037. Epub 2024 Feb 17. Cell. 2024. PMID: 38367616 Free PMC article. Clinical Trial.
SARS-CoV-2 evolution during prolonged infection in immunocompromised patients.
Marques AD, Graham-Wooten J, Fitzgerald AS, Sobel Leonard A, Cook EJ, Everett JK, Rodino KG, Moncla LH, Kelly BJ, Collman RG, Bushman FD. Marques AD, et al. Among authors: bushman fd. mBio. 2024 Mar 13;15(3):e0011024. doi: 10.1128/mbio.00110-24. Epub 2024 Feb 16. mBio. 2024. PMID: 38364100 Free PMC article.
Analysis of vector genome integrations in multicentric lymphoma after AAV gene therapy in a severe hemophilia A dog.
Van Gorder L, Doshi BS, Willis E, Nichols TC, Cook E, Everett JK, Merricks EP, Arruda VR, Bushman FD, Callan MB, Samelson-Jones BJ. Van Gorder L, et al. Among authors: bushman fd. Mol Ther Methods Clin Dev. 2023 Nov 14;31:101159. doi: 10.1016/j.omtm.2023.101159. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38094200 Free PMC article.
364 results