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Page 1
Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.
Crooks ET, Grimley SL, Cully M, Osawa K, Dekkers G, Saunders K, Rämisch S, Menis S, Schief WR, Doria-Rose N, Haynes B, Murrell B, Cale EM, Pegu A, Mascola JR, Vidarsson G, Binley JM. Crooks ET, et al. Among authors: grimley sl. PLoS Pathog. 2018 May 2;14(5):e1007024. doi: 10.1371/journal.ppat.1007024. eCollection 2018 May. PLoS Pathog. 2018. PMID: 29718999 Free PMC article.
Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.
Heydarchi B, Fong DS, Gao H, Salazar-Quiroz NA, Edwards JM, Gonelli CA, Grimley S, Aktepe TE, Mackenzie C, Wales WJ, van Gils MJ, Cupo A, Rouiller I, Gooley PR, Moore JP, Sanders RW, Montefiori D, Sethi A, Purcell DFJ. Heydarchi B, et al. Cell Rep Med. 2022 May 17;3(5):100635. doi: 10.1016/j.xcrm.2022.100635. Cell Rep Med. 2022. PMID: 35584627 Free PMC article.
Infrared Based Saliva Screening Test for COVID-19.
Wood BR, Kochan K, Bedolla DE, Salazar-Quiroz N, Grimley SL, Perez-Guaita D, Baker MJ, Vongsvivut J, Tobin MJ, Bambery KR, Christensen D, Pasricha S, Eden AK, Mclean A, Roy S, Roberts JA, Druce J, Williamson DA, McAuley J, Catton M, Purcell DFJ, Godfrey DI, Heraud P. Wood BR, et al. Among authors: grimley sl. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17102-17107. doi: 10.1002/anie.202104453. Epub 2021 Jun 29. Angew Chem Int Ed Engl. 2021. PMID: 34043272 Free PMC article.
Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay.
Lopez E, Haycroft ER, Adair A, Mordant FL, O'Neill MT, Pymm P, Redmond SJ, Lee WS, Gherardin NA, Wheatley AK, Juno JA, Selva KJ, Davis SK, Grimley SL, Harty L, Purcell DF, Subbarao K, Godfrey DI, Kent SJ, Tham WH, Chung AW. Lopez E, et al. Among authors: grimley sl. JCI Insight. 2021 Aug 23;6(16):e150012. doi: 10.1172/jci.insight.150012. JCI Insight. 2021. PMID: 34251356 Free PMC article.
A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2.
Fulford TS, Van H, Gherardin NA, Zheng S, Ciula M, Drummer HE, Redmond S, Tan HX, Boo I, Center RJ, Li F, Grimley SL, Wines BD, Nguyen THO, Mordant FL, Ellenberg P, Rowntree LC, Kedzierski L, Cheng AC, Doolan DL, Matthews G, Bond K, Hogarth PM, McQuilten Z, Subbarao K, Kedzierska K, Juno JA, Wheatley AK, Kent SJ, Williamson DA, Purcell DFJ, Anderson DA, Godfrey DI. Fulford TS, et al. Among authors: grimley sl. EBioMedicine. 2021 Dec;74:103729. doi: 10.1016/j.ebiom.2021.103729. Epub 2021 Dec 3. EBioMedicine. 2021. PMID: 34871960 Free PMC article.
Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2.
Pymm P, Redmond SJ, Dolezal O, Mordant F, Lopez E, Cooney JP, Davidson KC, Haycroft ER, Tan CW, Seneviratna R, Grimley SL, Purcell DFJ, Kent SJ, Wheatley AK, Wang LF, Leis A, Glukhova A, Pellegrini M, Chung AW, Subbarao K, Uldrich AP, Tham WH, Godfrey DI, Gherardin NA. Pymm P, et al. Among authors: grimley sl. iScience. 2022 Nov 18;25(11):105259. doi: 10.1016/j.isci.2022.105259. Epub 2022 Oct 4. iScience. 2022. PMID: 36213007 Free PMC article.
Air-Liquid-Interface Differentiated Human Nose Epithelium: A Robust Primary Tissue Culture Model of SARS-CoV-2 Infection.
Tran BM, Grimley SL, McAuley JL, Hachani A, Earnest L, Wong SL, Caly L, Druce J, Purcell DFJ, Jackson DC, Catton M, Nowell CJ, Leonie L, Deliyannis G, Waters SA, Torresi J, Vincan E. Tran BM, et al. Among authors: grimley sl. Int J Mol Sci. 2022 Jan 13;23(2):835. doi: 10.3390/ijms23020835. Int J Mol Sci. 2022. PMID: 35055020 Free PMC article.
Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Estcourt LJ, Turgeon AF, McQuilten ZK, McVerry BJ, Al-Beidh F, Annane D, Arabi YM, Arnold DM, Beane A, Bégin P, van Bentum-Puijk W, Berry LR, Bhimani Z, Birchall JE, Bonten MJM, Bradbury CA, Brunkhorst FM, Buxton M, Callum JL, Chassé M, Cheng AC, Cove ME, Daly J, Derde L, Detry MA, De Jong M, Evans A, Fergusson DA, Fish M, Fitzgerald M, Foley C, Goossens H, Gordon AC, Gosbell IB, Green C, Haniffa R, Harvala H, Higgins AM, Hills TE, Hoad VC, Horvat C, Huang DT, Hudson CL, Ichihara N, Laing E, Lamikanra AA, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, MacLennan S, Marshall J, McAuley DF, McDyer JF, McGlothlin A, McGuinness S, Miflin G, Montgomery S, Mouncey PR, Murthy S, Nichol A, Parke R, Parker JC, Priddee N, Purcell DFJ, Reyes LF, Richardson P, Robitaille N, Rowan KM, Rynne J, Saito H, Santos M, Saunders CT, Serpa Neto A, Seymour CW, Silversides JA, Tinmouth AA, Triulzi DJ, Turner AM, van de Veerdonk F, Walsh TS, Wood EM, Berry S, Lewis RJ, Menon DK, McArthur C, Zarychanski R, Angus DC, Webb SA, Roberts DJ, Shankar-Hari M. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2021 Nov 2;326(17):1690-1702. doi: 10.1001/jama.2021.18178. JAMA. 2021. PMID: 34606578 Free PMC article. Clinical Trial.
16 results