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Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.
Dravid SM, Erreger K, Yuan H, Nicholson K, Le P, Lyuboslavsky P, Almonte A, Murray E, Mosely C, Barber J, French A, Balster R, Murray TF, Traynelis SF. Dravid SM, et al. Among authors: le p. J Physiol. 2007 May 15;581(Pt 1):107-28. doi: 10.1113/jphysiol.2006.124958. Epub 2007 Feb 15. J Physiol. 2007. PMID: 17303642 Free PMC article.
Biased modulators of NMDA receptors control channel opening and ion selectivity.
Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, Liebeskind LS, Traynelis SF. Perszyk RE, et al. Among authors: le p. Nat Chem Biol. 2020 Feb;16(2):188-196. doi: 10.1038/s41589-019-0449-5. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959964 Free PMC article.
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors.
Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Mosley CA, et al. Among authors: le p. Bioorg Med Chem. 2009 Sep 1;17(17):6463-80. doi: 10.1016/j.bmc.2009.05.085. Epub 2009 Jul 5. Bioorg Med Chem. 2009. PMID: 19648014 Free PMC article.
Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.
Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, Liotta DC, Traynelis SF, Snyder JP. Tahirovic YA, et al. Among authors: le p. J Med Chem. 2008 Sep 25;51(18):5506-21. doi: 10.1021/jm8002153. J Med Chem. 2008. PMID: 18800760 Free PMC article.
976 results