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Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.
Bateman LA, Nguyen TB, Roberts AM, Miyamoto DK, Ku WM, Huffman TR, Petri Y, Heslin MJ, Contreras CM, Skibola CF, Olzmann JA, Nomura DK. Bateman LA, et al. Among authors: huffman tr. Chem Commun (Camb). 2017 Jun 29;53(53):7234-7237. doi: 10.1039/c7cc01480e. Chem Commun (Camb). 2017. PMID: 28352901 Free PMC article.
GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity.
Louie SM, Grossman EA, Crawford LA, Ding L, Camarda R, Huffman TR, Miyamoto DK, Goga A, Weerapana E, Nomura DK. Louie SM, et al. Among authors: huffman tr. Cell Chem Biol. 2016 May 19;23(5):567-578. doi: 10.1016/j.chembiol.2016.03.017. Epub 2016 May 12. Cell Chem Biol. 2016. PMID: 27185638 Free PMC article.
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.
Berdan CA, Ho R, Lehtola HS, To M, Hu X, Huffman TR, Petri Y, Altobelli CR, Demeulenaere SG, Olzmann JA, Maimone TJ, Nomura DK. Berdan CA, et al. Among authors: huffman tr. Cell Chem Biol. 2019 Jul 18;26(7):1027-1035.e22. doi: 10.1016/j.chembiol.2019.03.016. Epub 2019 May 9. Cell Chem Biol. 2019. PMID: 31080076 Free PMC article.
Hydroalkylation of Olefins To Form Quaternary Carbons.
Green SA, Huffman TR, McCourt RO, van der Puyl V, Shenvi RA. Green SA, et al. Among authors: huffman tr. J Am Chem Soc. 2019 May 15;141(19):7709-7714. doi: 10.1021/jacs.9b02844. Epub 2019 May 3. J Am Chem Soc. 2019. PMID: 31030508 Free PMC article.
Synthesis of (-)-Cotylenol, a 14-3-3 Molecular Glue Component.
Ting SI, Snelson DW, Huffman TR, Kuroo A, Sato R, Shenvi RA. Ting SI, et al. Among authors: huffman tr. J Am Chem Soc. 2023 Sep 20;145(37):20634-20645. doi: 10.1021/jacs.3c07849. Epub 2023 Sep 8. J Am Chem Soc. 2023. PMID: 37683289 Free PMC article.
A Case of Cardiac Arrest Due to Transcatheter Aortic Valve Infolding.
Mohammed F, Gubitosa JC, Huffman TR, Abdul-Waheed M, Rafeedheen R. Mohammed F, et al. Among authors: huffman tr. Cureus. 2023 Aug 21;15(8):e43847. doi: 10.7759/cureus.43847. eCollection 2023 Aug. Cureus. 2023. PMID: 37736431 Free PMC article.
13 results