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Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.
Bielinski SJ, Olson JE, Pathak J, Weinshilboum RM, Wang L, Lyke KJ, Ryu E, Targonski PV, Van Norstrand MD, Hathcock MA, Takahashi PY, McCormick JB, Johnson KJ, Maschke KJ, Rohrer Vitek CR, Ellingson MS, Wieben ED, Farrugia G, Morrisette JA, Kruckeberg KJ, Bruflat JK, Peterson LM, Blommel JH, Skierka JM, Ferber MJ, Black JL, Baudhuin LM, Klee EW, Ross JL, Veldhuizen TL, Schultz CG, Caraballo PJ, Freimuth RR, Chute CG, Kullo IJ. Bielinski SJ, et al. Mayo Clin Proc. 2014 Jan;89(1):25-33. doi: 10.1016/j.mayocp.2013.10.021. Mayo Clin Proc. 2014. PMID: 24388019 Free PMC article.
Biobanks and personalized medicine.
Olson JE, Bielinski SJ, Ryu E, Winkler EM, Takahashi PY, Pathak J, Cerhan JR. Olson JE, et al. Among authors: bielinski sj. Clin Genet. 2014 Jul;86(1):50-5. doi: 10.1111/cge.12370. Epub 2014 Mar 27. Clin Genet. 2014. PMID: 24588254 Free PMC article. Review.
Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems.
Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, Leppig KA, Li R, Lin S, Manzi S, Mejia AR, Pacheco JA, Pan V, Pathak J, Perry CL, Peterson JF, Prows CA, Ralston J, Rasmussen LV, Ritchie MD, Sadhasivam S, Scott SA, Smith M, Vega A, Vinks AA, Volpi S, Wolf WA, Bottinger E, Chisholm RL, Chute CG, Haines JL, Harley JB, Keating B, Holm IA, Kullo IJ, Jarvik GP, Larson EB, Manolio T, McCarty CA, Nickerson DA, Scherer SE, Williams MS, Roden DM, Denny JC. Rasmussen-Torvik LJ, et al. Among authors: bielinski sj. Clin Pharmacol Ther. 2014 Oct;96(4):482-9. doi: 10.1038/clpt.2014.137. Epub 2014 Jun 24. Clin Pharmacol Ther. 2014. PMID: 24960519 Free PMC article.
Clinical Decision Support to Implement CYP2D6 Drug-Gene Interaction.
Caraballo PJ, Parkulo M, Blair D, Elliott M, Schultz C, Sutton J, Rao P, Bruflat J, Bleimeyer R, Crooks J, Gabrielson D, Nicholson W, Rohrer Vitek C, Wix K, Bielinski SJ, Pathak J, Kullo I. Caraballo PJ, et al. Among authors: bielinski sj. Stud Health Technol Inform. 2015;216:946. Stud Health Technol Inform. 2015. PMID: 26262248
Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network.
Bush WS, Crosslin DR, Owusu-Obeng A, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, Kitchner T, Manzi S, Mejia AR, Pan V, Perry CL, Peterson JF, Prows CA, Ralston J, Scott SA, Scrol A, Smith M, Stallings SC, Veldhuizen T, Wolf W, Volpi S, Wiley K, Li R, Manolio T, Bottinger E, Brilliant MH, Carey D, Chisholm RL, Chute CG, Haines JL, Hakonarson H, Harley JB, Holm IA, Kullo IJ, Jarvik GP, Larson EB, McCarty CA, Williams MS, Denny JC, Rasmussen-Torvik LJ, Roden DM, Ritchie MD. Bush WS, et al. Among authors: bielinski sj. Clin Pharmacol Ther. 2016 Aug;100(2):160-9. doi: 10.1002/cpt.350. Epub 2016 Jun 1. Clin Pharmacol Ther. 2016. PMID: 26857349 Free PMC article.
Preemptive Pharmacogenomic Testing for Precision Medicine: A Comprehensive Analysis of Five Actionable Pharmacogenomic Genes Using Next-Generation DNA Sequencing and a Customized CYP2D6 Genotyping Cascade.
Ji Y, Skierka JM, Blommel JH, Moore BE, VanCuyk DL, Bruflat JK, Peterson LM, Veldhuizen TL, Fadra N, Peterson SE, Lagerstedt SA, Train LJ, Baudhuin LM, Klee EW, Ferber MJ, Bielinski SJ, Caraballo PJ, Weinshilboum RM, Black JL 3rd. Ji Y, et al. Among authors: bielinski sj. J Mol Diagn. 2016 May;18(3):438-445. doi: 10.1016/j.jmoldx.2016.01.003. Epub 2016 Mar 3. J Mol Diagn. 2016. PMID: 26947514 Free PMC article.
Improvement in Cardiovascular Risk Prediction with Electronic Health Records.
Pike MM, Decker PA, Larson NB, St Sauver JL, Takahashi PY, Roger VL, Rocca WA, Miller VM, Olson JE, Pathak J, Bielinski SJ. Pike MM, et al. Among authors: bielinski sj. J Cardiovasc Transl Res. 2016 Jun;9(3):214-222. doi: 10.1007/s12265-016-9687-z. Epub 2016 Mar 9. J Cardiovasc Transl Res. 2016. PMID: 26960568 Free PMC article.
Integrating Pharmacogenomics into Clinical Practice: Promise vs Reality.
St Sauver JL, Bielinski SJ, Olson JE, Bell EJ, Mc Gree ME, Jacobson DJ, McCormick JB, Caraballo PJ, Takahashi PY, Roger VL, Rohrer Vitek CR. St Sauver JL, et al. Among authors: bielinski sj. Am J Med. 2016 Oct;129(10):1093-1099.e1. doi: 10.1016/j.amjmed.2016.04.009. Epub 2016 May 5. Am J Med. 2016. PMID: 27155109 Free PMC article.
Multidisciplinary model to implement pharmacogenomics at the point of care.
Caraballo PJ, Hodge LS, Bielinski SJ, Stewart AK, Farrugia G, Schultz CG, Rohrer-Vitek CR, Olson JE, St Sauver JL, Roger VL, Parkulo MA, Kullo IJ, Nicholson WT, Elliott MA, Black JL, Weinshilboum RM. Caraballo PJ, et al. Among authors: bielinski sj. Genet Med. 2017 Apr;19(4):421-429. doi: 10.1038/gim.2016.120. Epub 2016 Sep 22. Genet Med. 2017. PMID: 27657685 Free PMC article.
175 results