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IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis.
Eslam M, McLeod D, Kelaeng KS, Mangia A, Berg T, Thabet K, Irving WL, Dore GJ, Sheridan D, Grønbæk H, Abate ML, Hartmann R, Bugianesi E, Spengler U, Rojas A, Booth DR, Weltman M, Mollison L, Cheng W, Riordan S, Mahajan H, Fischer J, Nattermann J, Douglas MW, Liddle C, Powell E, Romero-Gomez M, George J; International Liver Disease Genetics Consortium (ILDGC). Eslam M, et al. Among authors: berg t. Nat Genet. 2017 May;49(5):795-800. doi: 10.1038/ng.3836. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394349 Free article.
The tandem-repeat polymorphism of the DC-SIGNR gene in HCV infection.
Nattermann J, Ahlenstiel G, Berg T, Feldmann G, Nischalke HD, Müller T, Rockstroh J, Woitas R, Sauerbruch T, Spengler U. Nattermann J, et al. Among authors: berg t. J Viral Hepat. 2006 Jan;13(1):42-6. doi: 10.1111/j.1365-2893.2005.00652.x. J Viral Hepat. 2006. PMID: 16364081
Induction of interleukin-6 by hepatitis C virus core protein in hepatitis C-associated mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma.
Feldmann G, Nischalke HD, Nattermann J, Banas B, Berg T, Teschendorf C, Schmiegel W, Dührsen U, Halangk J, Iwan A, Sauerbruch T, Caselmann WH, Spengler U. Feldmann G, et al. Among authors: berg t. Clin Cancer Res. 2006 Aug 1;12(15):4491-8. doi: 10.1158/1078-0432.CCR-06-0154. Clin Cancer Res. 2006. PMID: 16899594
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.
Suppiah V, Moldovan M, Ahlenstiel G, Berg T, Weltman M, Abate ML, Bassendine M, Spengler U, Dore GJ, Powell E, Riordan S, Sheridan D, Smedile A, Fragomeli V, Müller T, Bahlo M, Stewart GJ, Booth DR, George J. Suppiah V, et al. Among authors: berg t. Nat Genet. 2009 Oct;41(10):1100-4. doi: 10.1038/ng.447. Epub 2009 Sep 13. Nat Genet. 2009. PMID: 19749758
The HLA-E(R)/HLA-E(R) genotype affects the natural course of hepatitis C virus (HCV) infection and is associated with HLA-E-restricted recognition of an HCV-derived peptide by interferon-gamma-secreting human CD8(+) T cells.
Schulte D, Vogel M, Langhans B, Krämer B, Körner C, Nischalke HD, Steinberg V, Michalk M, Berg T, Rockstroh JK, Sauerbruch T, Spengler U, Nattermann J. Schulte D, et al. Among authors: berg t. J Infect Dis. 2009 Nov 1;200(9):1397-401. doi: 10.1086/605889. J Infect Dis. 2009. PMID: 19780673
The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C.
Nischalke HD, Coenen M, Berger C, Aldenhoff K, Müller T, Berg T, Krämer B, Körner C, Odenthal M, Schulze F, Grünhage F, Nattermann J, Sauerbruch T, Spengler U. Nischalke HD, et al. Among authors: berg t. Int J Cancer. 2012 Mar 15;130(6):1470-5. doi: 10.1002/ijc.26143. Epub 2011 Jun 18. Int J Cancer. 2012. PMID: 21500195 Free article.
The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.
Nattermann J, Timm J, Nischalke HD, Olbrich A, Michalk M, Tillmann HL, Berg T, Wedemeyer H, Tenckhoff H, Wiese M, Kullig U, Göbel U, Capka E, Schiefke I, Güthof W, Grüngreiff K, König I, Roggendorf M, Sauerbruch T, Spengler U; East German HCV Study Group. Nattermann J, et al. Among authors: berg t. J Hepatol. 2011 Dec;55(6):1201-6. doi: 10.1016/j.jhep.2011.03.011. Epub 2011 Apr 13. J Hepatol. 2011. PMID: 21703201
Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort.
Smith KR, Suppiah V, O'Connor K, Berg T, Weltman M, Abate ML, Spengler U, Bassendine M, Matthews G, Irving WL, Powell E, Riordan S, Ahlenstiel G, Stewart GJ, Bahlo M, George J, Booth DR; International Hepatitis C Genetics Consortium (IHCGC). Smith KR, et al. Among authors: berg t. Genome Med. 2011 Aug 31;3(8):57. doi: 10.1186/gm273. Genome Med. 2011. PMID: 21884576 Free PMC article.
2,213 results