Zoncu R - Search Results

1

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy.

Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, Nomura DK, Olzmann JA. Nguyen TB, et al. Among authors: zoncu r. Dev Cell. 2017 Jul 10;42(1):9-21.e5. doi: 10.1016/j.devcel.2017.06.003. Dev Cell. 2017. PMID: 28697336 Free PMC article.

2

The lysosome as a command-and-control center for cellular metabolism.

Lim CY, Zoncu R. Lim CY, et al. Among authors: zoncu r. J Cell Biol. 2016 Sep 12;214(6):653-64. doi: 10.1083/jcb.201607005. J Cell Biol. 2016. PMID: 27621362 Free PMC article. Review.

3

Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.

Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. Castellano BM, et al. Among authors: zoncu r. Science. 2017 Mar 24;355(6331):1306-1311. doi: 10.1126/science.aag1417. Science. 2017. PMID: 28336668 Free PMC article.

4

Emerging Roles for the Lysosome in Lipid Metabolism.

Thelen AM, Zoncu R. Thelen AM, et al. Among authors: zoncu r. Trends Cell Biol. 2017 Nov;27(11):833-850. doi: 10.1016/j.tcb.2017.07.006. Epub 2017 Aug 30. Trends Cell Biol. 2017. PMID: 28838620 Free PMC article. Review.

5

Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors.

De Leon JA, Qiu J, Nicolai CJ, Counihan JL, Barry KC, Xu L, Lawrence RE, Castellano BM, Zoncu R, Nomura DK, Luo ZQ, Vance RE. De Leon JA, et al. Among authors: zoncu r. Cell Rep. 2017 Nov 21;21(8):2031-2038. doi: 10.1016/j.celrep.2017.10.088. Cell Rep. 2017. PMID: 29166595 Free PMC article.

6

Finding Sugar in the Pantry: How Galectins Detect and Signal Lysosomal Damage.

Shin HR, Zoncu R. Shin HR, et al. Among authors: zoncu r. Mol Cell. 2018 Apr 5;70(1):5-7. doi: 10.1016/j.molcel.2018.03.017. Mol Cell. 2018. PMID: 29625038 Free article.

7

Covalent targeting of the vacuolar H⁺-ATPase activates autophagy via mTORC1 inhibition.

Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK. Chung CY, et al. Among authors: zoncu r. Nat Chem Biol. 2019 Aug;15(8):776-785. doi: 10.1038/s41589-019-0308-4. Epub 2019 Jul 8. Nat Chem Biol. 2019. PMID: 31285595 Free PMC article.

8

ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C.

Lim CY, Davis OB, Shin HR, Zhang J, Berdan CA, Jiang X, Counihan JL, Ory DS, Nomura DK, Zoncu R. Lim CY, et al. Among authors: zoncu r. Nat Cell Biol. 2019 Oct;21(10):1206-1218. doi: 10.1038/s41556-019-0391-5. Epub 2019 Sep 23. Nat Cell Biol. 2019. PMID: 31548609 Free PMC article.

9

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Bersuker K, et al. Among authors: zoncu r. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. Nature. 2019. PMID: 31634900 Free PMC article.

10

The Lysosome at the Intersection of Cellular Growth and Destruction.

Shin HR, Zoncu R. Shin HR, et al. Among authors: zoncu r. Dev Cell. 2020 Jul 20;54(2):226-238. doi: 10.1016/j.devcel.2020.06.010. Epub 2020 Jun 30. Dev Cell. 2020. PMID: 32610045 Free PMC article. Review.

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