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Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1.
Gemma S, Giovani S, Brindisi M, Tripaldi P, Brogi S, Savini L, Fiorini I, Novellino E, Butini S, Campiani G, Penzo M, Blackman MJ. Gemma S, et al. Among authors: brindisi m. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5317-21. doi: 10.1016/j.bmcl.2012.06.023. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22796182
Rational design of the first difluorostatone-based PfSUB1 inhibitors.
Giovani S, Penzo M, Brogi S, Brindisi M, Gemma S, Novellino E, Savini L, Blackman MJ, Campiani G, Butini S. Giovani S, et al. Among authors: brindisi m. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3582-6. doi: 10.1016/j.bmcl.2014.05.044. Epub 2014 May 23. Bioorg Med Chem Lett. 2014. PMID: 24909083
Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand.
Ghosh AK, Brindisi M, Yen YC, Xu X, Huang X, Devasamudram T, Bilcer G, Lei H, Koelsch G, Mesecar AD, Tang J. Ghosh AK, et al. Among authors: brindisi m. Bioorg Med Chem Lett. 2015 Feb 1;25(3):668-72. doi: 10.1016/j.bmcl.2014.11.087. Epub 2014 Dec 6. Bioorg Med Chem Lett. 2015. PMID: 25537272 Free PMC article.
Organic carbamates in drug design and medicinal chemistry.
Ghosh AK, Brindisi M. Ghosh AK, et al. Among authors: brindisi m. J Med Chem. 2015 Apr 9;58(7):2895-940. doi: 10.1021/jm501371s. Epub 2015 Jan 7. J Med Chem. 2015. PMID: 25565044 Free PMC article. Review.
Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.
Ghosh AK, Brindisi M, Nyalapatla PR, Takayama J, Ella-Menye JR, Yashchuk S, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H. Ghosh AK, et al. Among authors: brindisi m. Bioorg Med Chem. 2017 Oct 1;25(19):5114-5127. doi: 10.1016/j.bmc.2017.04.005. Epub 2017 Apr 9. Bioorg Med Chem. 2017. PMID: 28434781 Free PMC article.
176 results