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Nicotine Metabolism-informed Care for Smoking Cessation: A Pilot Precision RCT.
Wells QS, Freiberg MS, Greevy RA Jr, Tyndale RF, Kundu S, Duncan MS, King S, Abney L, Scoville E, Beaulieu DB, Gatskie V, Tindle HA. Wells QS, et al. Among authors: tyndale rf. Nicotine Tob Res. 2018 Nov 15;20(12):1489-1496. doi: 10.1093/ntr/ntx235. Nicotine Tob Res. 2018. PMID: 29059367 Free PMC article. Clinical Trial.
A common genetic defect in nicotine metabolism decreases risk for dependence and lowers cigarette consumption.
Tyndale RF, Pianezza ML, Sellers EM. Tyndale RF, et al. Nicotine Tob Res. 1999;1 Suppl 2:S63-7; discussion S69-70. doi: 10.1080/14622299050011831. Nicotine Tob Res. 1999. PMID: 11768189 Review.
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if dependent, how impairment of the CYP2A6 gene function decreases the number of cigarettes consumed by smokers (Pianezza M, Sellers EM, Tyndale …
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if depend …
Non-nicotinic therapies for smoking cessation.
Siu EC, Tyndale RF. Siu EC, et al. Among authors: tyndale rf. Annu Rev Pharmacol Toxicol. 2007;47:541-64. doi: 10.1146/annurev.pharmtox.47.120505.105354. Annu Rev Pharmacol Toxicol. 2007. PMID: 17209799 Review.
Molecular genetics of nicotine metabolism.
Mwenifumbo JC, Tyndale RF. Mwenifumbo JC, et al. Among authors: tyndale rf. Handb Exp Pharmacol. 2009;(192):235-59. doi: 10.1007/978-3-540-69248-5_9. Handb Exp Pharmacol. 2009. PMID: 19184652 Review.
441 results