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Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
Wutz G, Várnai C, Nagasaka K, Cisneros DA, Stocsits RR, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain MJ, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM. Wutz G, et al. Among authors: fraser p. EMBO J. 2017 Dec 15;36(24):3573-3599. doi: 10.15252/embj.201798004. Epub 2017 Dec 7. EMBO J. 2017. PMID: 29217591 Free PMC article.
Activation of the beta globin locus by transcription factors and chromatin modifiers.
McMorrow T, van den Wijngaard A, Wollenschlaeger A, van de Corput M, Monkhorst K, Trimborn T, Fraser P, van Lohuizen M, Jenuwein T, Djabali M, Philipsen S, Grosveld F, Milot E. McMorrow T, et al. Among authors: fraser p. EMBO J. 2000 Sep 15;19(18):4986-96. doi: 10.1093/emboj/19.18.4986. EMBO J. 2000. PMID: 10990462 Free PMC article.
Interchromosomal huddle kickstarts antiviral defense.
Schoenfelder S, Fraser P. Schoenfelder S, et al. Among authors: fraser p. Cell. 2008 Jul 11;134(1):14-6. doi: 10.1016/j.cell.2008.06.041. Cell. 2008. PMID: 18614003 Free article.
The transcriptional interactome: gene expression in 3D.
Schoenfelder S, Clay I, Fraser P. Schoenfelder S, et al. Among authors: fraser p. Curr Opin Genet Dev. 2010 Apr;20(2):127-33. doi: 10.1016/j.gde.2010.02.002. Epub 2010 Mar 6. Curr Opin Genet Dev. 2010. PMID: 20211559 Review.
Transcription factories and nuclear organization of the genome.
Eskiw CH, Cope NF, Clay I, Schoenfelder S, Nagano T, Fraser P. Eskiw CH, et al. Among authors: fraser p. Cold Spring Harb Symp Quant Biol. 2010;75:501-6. doi: 10.1101/sqb.2010.75.046. Epub 2011 Apr 5. Cold Spring Harb Symp Quant Biol. 2010. PMID: 21467135
Nuclear RNA sequencing of the mouse erythroid cell transcriptome.
Mitchell JA, Clay I, Umlauf D, Chen CY, Moir CA, Eskiw CH, Schoenfelder S, Chakalova L, Nagano T, Fraser P. Mitchell JA, et al. Among authors: fraser p. PLoS One. 2012;7(11):e49274. doi: 10.1371/journal.pone.0049274. Epub 2012 Nov 29. PLoS One. 2012. PMID: 23209567 Free PMC article.
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure.
Nagano T, Lubling Y, Stevens TJ, Schoenfelder S, Yaffe E, Dean W, Laue ED, Tanay A, Fraser P. Nagano T, et al. Among authors: fraser p. Nature. 2013 Oct 3;502(7469):59-64. doi: 10.1038/nature12593. Epub 2013 Sep 25. Nature. 2013. PMID: 24067610 Free PMC article.
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.
Dryden NH, Broome LR, Dudbridge F, Johnson N, Orr N, Schoenfelder S, Nagano T, Andrews S, Wingett S, Kozarewa I, Assiotis I, Fenwick K, Maguire SL, Campbell J, Natrajan R, Lambros M, Perrakis E, Ashworth A, Fraser P, Fletcher O. Dryden NH, et al. Among authors: fraser p. Genome Res. 2014 Nov;24(11):1854-68. doi: 10.1101/gr.175034.114. Epub 2014 Aug 13. Genome Res. 2014. PMID: 25122612 Free PMC article.
872 results