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Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, Bono J, Carracedo A, Alimonti A. Chen J, et al. Among authors: carracedo a. Nat Genet. 2018 Feb;50(2):219-228. doi: 10.1038/s41588-017-0026-3. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335542 Free PMC article.
Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Nardella C, et al. Among authors: carracedo a. Sci Signal. 2009 Jan 27;2(55):ra2. doi: 10.1126/scisignal.2000189. Sci Signal. 2009. PMID: 19176516 Free PMC article.
Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Chen Z, et al. Among authors: carracedo a. Sci Signal. 2009 Aug 18;2(84):ra44. doi: 10.1126/scisignal.2000053. Sci Signal. 2009. PMID: 19690330 Free PMC article.
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP. Alimonti A, et al. Among authors: carracedo a. J Clin Invest. 2010 Mar;120(3):681-93. doi: 10.1172/JCI40535. Epub 2010 Feb 8. J Clin Invest. 2010. PMID: 20197621 Free PMC article.
Subtle variations in Pten dose determine cancer susceptibility.
Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J, Pandolfi PP. Alimonti A, et al. Among authors: carracedo a. Nat Genet. 2010 May;42(5):454-8. doi: 10.1038/ng.556. Epub 2010 Apr 18. Nat Genet. 2010. PMID: 20400965 Free PMC article.
PTEN level in tumor suppression: how much is too little?
Carracedo A, Alimonti A, Pandolfi PP. Carracedo A, et al. Cancer Res. 2011 Feb 1;71(3):629-33. doi: 10.1158/0008-5472.CAN-10-2488. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266353 Free PMC article. Review.
918 results