Ziegler S - Search Results

1

Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.

Höing S, Yeh TY, Baumann M, Martinez NE, Habenberger P, Kremer L, Drexler HCA, Küchler P, Reinhardt P, Choidas A, Zischinsky ML, Zischinsky G, Nandini S, Ledray AP, Ketcham SA, Reinhardt L, Abo-Rady M, Glatza M, King SJ, Nussbaumer P, Ziegler S, Klebl B, Schroer TA, Schöler HR, Waldmann H, Sterneckert J. Höing S, et al. Among authors: ziegler s. Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6. doi: 10.1016/j.chembiol.2017.12.014. Epub 2018 Jan 27. Cell Chem Biol. 2018. PMID: 29396292 Free PMC article.

2

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products.

Antonchick AP, Gerding-Reimers C, Catarinella M, Schürmann M, Preut H, Ziegler S, Rauh D, Waldmann H. Antonchick AP, et al. Among authors: ziegler s. Nat Chem. 2010 Sep;2(9):735-40. doi: 10.1038/nchem.730. Epub 2010 Jul 11. Nat Chem. 2010. PMID: 20729892

3

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.

Radtke L, Willot M, Sun H, Ziegler S, Sauerland S, Strohmann C, Fröhlich R, Habenberger P, Waldmann H, Christmann M. Radtke L, et al. Among authors: ziegler s. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3998-4002. doi: 10.1002/anie.201007790. Epub 2011 Mar 29. Angew Chem Int Ed Engl. 2011. PMID: 21472928 No abstract available.

4

Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

Dückert H, Pries V, Khedkar V, Menninger S, Bruss H, Bird AW, Maliga Z, Brockmeyer A, Janning P, Hyman A, Grimme S, Schürmann M, Preut H, Hübel K, Ziegler S, Kumar K, Waldmann H. Dückert H, et al. Among authors: ziegler s. Nat Chem Biol. 2011 Dec 25;8(2):179-84. doi: 10.1038/nchembio.758. Nat Chem Biol. 2011. PMID: 22198731

5

A natural product inspired tetrahydropyran collection yields mitosis modulators that synergistically target CSE1L and tubulin.

Voigt T, Gerding-Reimers C, Ngoc Tran TT, Bergmann S, Lachance H, Schölermann B, Brockmeyer A, Janning P, Ziegler S, Waldmann H. Voigt T, et al. Among authors: ziegler s. Angew Chem Int Ed Engl. 2013 Jan 2;52(1):410-4. doi: 10.1002/anie.201205728. Epub 2012 Oct 18. Angew Chem Int Ed Engl. 2013. PMID: 23080551

6

Biology-oriented synthesis of a tetrahydroisoquinoline-based compound collection targeting microtubule polymerization.

Zimmermann TJ, Roy S, Martinez NE, Ziegler S, Hedberg C, Waldmann H. Zimmermann TJ, et al. Among authors: ziegler s. Chembiochem. 2013 Feb 11;14(3):295-300. doi: 10.1002/cbic.201200711. Epub 2013 Jan 31. Chembiochem. 2013. PMID: 23364933

7

Target identification for small bioactive molecules: finding the needle in the haystack.

Ziegler S, Pries V, Hedberg C, Waldmann H. Ziegler S, et al. Angew Chem Int Ed Engl. 2013 Mar 4;52(10):2744-92. doi: 10.1002/anie.201208749. Epub 2013 Feb 18. Angew Chem Int Ed Engl. 2013. PMID: 23418026 Review.

8

Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection.

Takayama H, Jia ZJ, Kremer L, Bauer JO, Strohmann C, Ziegler S, Antonchick AP, Waldmann H. Takayama H, et al. Among authors: ziegler s. Angew Chem Int Ed Engl. 2013 Nov 18;52(47):12404-8. doi: 10.1002/anie.201306948. Epub 2013 Oct 2. Angew Chem Int Ed Engl. 2013. PMID: 24115579

9

An enantioselective inverse-electron-demand imino Diels-Alder reaction.

Eschenbrenner-Lux V, Küchler P, Ziegler S, Kumar K, Waldmann H. Eschenbrenner-Lux V, et al. Among authors: ziegler s. Angew Chem Int Ed Engl. 2014 Feb 17;53(8):2134-7. doi: 10.1002/anie.201309022. Epub 2014 Jan 27. Angew Chem Int Ed Engl. 2014. PMID: 24470427

10

Podoverine A--a novel microtubule destabilizing natural product from the Podophyllum species.

Tran TT, Gerding-Reimers C, Schölermann B, Stanitzki B, Henkel T, Waldmann H, Ziegler S. Tran TT, et al. Among authors: ziegler s. Bioorg Med Chem. 2014 Sep 15;22(18):5110-6. doi: 10.1016/j.bmc.2014.01.039. Epub 2014 Feb 1. Bioorg Med Chem. 2014. PMID: 24530033

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