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Gi- and Gs-coupled GPCRs show different modes of G-protein binding.
Van Eps N, Altenbach C, Caro LN, Latorraca NR, Hollingsworth SA, Dror RO, Ernst OP, Hubbell WL. Van Eps N, et al. Among authors: dror ro. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2383-2388. doi: 10.1073/pnas.1721896115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463720 Free PMC article.
Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK. Rosenbaum DM, et al. Among authors: dror ro. Nature. 2011 Jan 13;469(7329):236-40. doi: 10.1038/nature09665. Nature. 2011. PMID: 21228876 Free PMC article.
Pathway and mechanism of drug binding to G-protein-coupled receptors.
Dror RO, Pan AC, Arlow DH, Borhani DW, Maragakis P, Shan Y, Xu H, Shaw DE. Dror RO, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13118-23. doi: 10.1073/pnas.1104614108. Epub 2011 Jul 21. Proc Natl Acad Sci U S A. 2011. PMID: 21778406 Free PMC article.
GPCR Dynamics: Structures in Motion.
Latorraca NR, Venkatakrishnan AJ, Dror RO. Latorraca NR, et al. Among authors: dror ro. Chem Rev. 2017 Jan 11;117(1):139-155. doi: 10.1021/acs.chemrev.6b00177. Epub 2016 Sep 13. Chem Rev. 2017. PMID: 27622975 Free article. Review.
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE. Zhou XE, et al. Among authors: dror ro. Cell. 2017 Jul 27;170(3):457-469.e13. doi: 10.1016/j.cell.2017.07.002. Cell. 2017. PMID: 28753425 Free PMC article.
118 results