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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NG, Herrera Gómez IG, Fuente-Martin E, López-Noriega L, Mellado-Gil JM, Romero-Zerbo SY, Baquié M, Lachaud CC, Stifter K, Perdomo G, Bugliani M, De Tata V, Bosco D, Parnaud G, Pozo D, Hmadcha A, Florido JP, Toscano MG, de Haan P, Schoonjans K, Sánchez Palazón L, Marchetti P, Schirmbeck R, Martín-Montalvo A, Meda P, Soria B, Bermúdez-Silva FJ, St-Onge L, Gauthier BR. Cobo-Vuilleumier N, et al. Among authors: bugliani m. Nat Commun. 2018 Apr 16;9(1):1488. doi: 10.1038/s41467-018-03943-0. Nat Commun. 2018. PMID: 29662071 Free PMC article.
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.
Mellado-Gil JM, Fuente-Martín E, Lorenzo PI, Cobo-Vuilleumier N, López-Noriega L, Martín-Montalvo A, Gómez IGH, Ceballos-Chávez M, Gómez-Jaramillo L, Campos-Caro A, Romero-Zerbo SY, Rodríguez-Comas J, Servitja JM, Rojo-Martinez G, Hmadcha A, Soria B, Bugliani M, Marchetti P, Bérmudez-Silva FJ, Reyes JC, Aguilar-Diosdado M, Gauthier BR. Mellado-Gil JM, et al. Among authors: bugliani m. Cell Death Dis. 2018 Feb 15;9(3):279. doi: 10.1038/s41419-018-0272-z. Cell Death Dis. 2018. PMID: 29449530 Free PMC article.
Optical control of insulin release using a photoswitchable sulfonylurea.
Broichhagen J, Schönberger M, Cork SC, Frank JA, Marchetti P, Bugliani M, Shapiro AM, Trapp S, Rutter GA, Hodson DJ, Trauner D. Broichhagen J, et al. Among authors: bugliani m. Nat Commun. 2014 Oct 14;5:5116. doi: 10.1038/ncomms6116. Nat Commun. 2014. PMID: 25311795 Free PMC article.
Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes.
Marchetti P, Bugliani M, De Tata V, Suleiman M, Marselli L. Marchetti P, et al. Among authors: bugliani m. Front Cell Dev Biol. 2017 May 23;5:55. doi: 10.3389/fcell.2017.00055. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 28589121 Free PMC article. Review.
The pancreatic beta cells in human type 2 diabetes.
Marchetti P, Bugliani M, Boggi U, Masini M, Marselli L. Marchetti P, et al. Among authors: bugliani m. Adv Exp Med Biol. 2012;771:288-309. doi: 10.1007/978-1-4614-5441-0_22. Adv Exp Med Biol. 2012. PMID: 23393686 Review.
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: bugliani m. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
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