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Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP-305, a novel farnesoid X receptor agonist.
Erstad DJ, Farrar CT, Ghoshal S, Masia R, Ferreira DS, Chen YI, Choi JK, Wei L, Waghorn PA, Rotile NJ, Tu C, Graham-O'Regan KA, Sojoodi M, Li S, Li Y, Wang G, Corey KE, Or YS, Jiang L, Tanabe KK, Caravan P, Fuchs BC. Erstad DJ, et al. Among authors: or ys. Hepatol Commun. 2018 May 21;2(7):821-835. doi: 10.1002/hep4.1193. eCollection 2018 Jul. Hepatol Commun. 2018. PMID: 30027140 Free PMC article.
Preclinical Profile and Clinical Efficacy of a Novel Hepatitis C Virus NS5A Inhibitor, EDP-239.
Owens CM, Brasher BB, Polemeropoulos A, Rhodin MH, McAllister N, Peng X, Wang C, Ying L, Cao H, Lawitz E, Poordad F, Rondon J, Box TD, Zeuzem S, Buggisch P, Lin K, Qiu YL, Jiang L, Colvin R, Or YS. Owens CM, et al. Among authors: or ys. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6207-15. doi: 10.1128/AAC.00808-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27503640 Free PMC article. Clinical Trial.
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir.
Ng TI, Tripathi R, Reisch T, Lu L, Middleton T, Hopkins TA, Pithawalla R, Irvin M, Dekhtyar T, Krishnan P, Schnell G, Beyer J, McDaniel KF, Ma J, Wang G, Jiang LJ, Or YS, Kempf D, Pilot-Matias T, Collins C. Ng TI, et al. Among authors: or ys. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01620-17. doi: 10.1128/AAC.01620-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29084747 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35553604
EDP-938, a novel nucleoprotein inhibitor of respiratory syncytial virus, demonstrates potent antiviral activities in vitro and in a non-human primate model.
Rhodin MHJ, McAllister NV, Castillo J, Noton SL, Fearns R, Kim IJ, Yu J, Blaisdell TP, Panarese J, Shook BC, Or YS, Goodwin B, Lin K. Rhodin MHJ, et al. Among authors: or ys. PLoS Pathog. 2021 Mar 15;17(3):e1009428. doi: 10.1371/journal.ppat.1009428. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720995 Free PMC article.
41 results