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Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.
Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, Spedding M, Louis C, Martin OR, Millan MJ. Boland B, et al. Among authors: henriques a. Nat Rev Drug Discov. 2018 Sep;17(9):660-688. doi: 10.1038/nrd.2018.109. Epub 2018 Aug 17. Nat Rev Drug Discov. 2018. PMID: 30116051 Free PMC article. Review.
GM1 ganglioside exerts protective effects against glutamate-excitotoxicity via its oligosaccharide in wild-type and amyotrophic lateral sclerosis motor neurons.
Lunghi G, Di Biase E, Carsana EV, Henriques A, Callizot N, Mauri L, Ciampa MG, Mari L, Loberto N, Aureli M, Sonnino S, Spedding M, Chiricozzi E, Fazzari M. Lunghi G, et al. Among authors: henriques a. FEBS Open Bio. 2023 Dec;13(12):2324-2341. doi: 10.1002/2211-5463.13727. Epub 2023 Nov 15. FEBS Open Bio. 2023. PMID: 37885330 Free PMC article.
Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase.
Henriques A, Croixmarie V, Priestman DA, Rosenbohm A, Dirrig-Grosch S, D'Ambra E, Huebecker M, Hussain G, Boursier-Neyret C, Echaniz-Laguna A, Ludolph AC, Platt FM, Walther B, Spedding M, Loeffler JP, Gonzalez De Aguilar JL. Henriques A, et al. Hum Mol Genet. 2015 Dec 20;24(25):7390-405. doi: 10.1093/hmg/ddv439. Epub 2015 Oct 19. Hum Mol Genet. 2015. PMID: 26483191 Free PMC article.
AZP2006, a new promising treatment for Alzheimer's and related diseases.
Callizot N, Estrella C, Burlet S, Henriques A, Brantis C, Barrier M, Campanari ML, Verwaerde P. Callizot N, et al. Among authors: henriques a. Sci Rep. 2021 Aug 19;11(1):16806. doi: 10.1038/s41598-021-94708-1. Sci Rep. 2021. PMID: 34413330 Free PMC article.
771 results