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Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.
Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, Spedding M, Louis C, Martin OR, Millan MJ. Boland B, et al. Among authors: rubinsztein dc. Nat Rev Drug Discov. 2018 Sep;17(9):660-688. doi: 10.1038/nrd.2018.109. Epub 2018 Aug 17. Nat Rev Drug Discov. 2018. PMID: 30116051 Free PMC article. Review.
Potential therapeutic applications of autophagy.
Rubinsztein DC, Gestwicki JE, Murphy LO, Klionsky DJ. Rubinsztein DC, et al. Nat Rev Drug Discov. 2007 Apr;6(4):304-12. doi: 10.1038/nrd2272. Nat Rev Drug Discov. 2007. PMID: 17396135 Review.
Clearance of mutant aggregate-prone proteins by autophagy.
Ravikumar B, Sarkar S, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Methods Mol Biol. 2008;445:195-211. doi: 10.1007/978-1-59745-157-4_13. Methods Mol Biol. 2008. PMID: 18425452
A comprehensive glossary of autophagy-related molecules and processes.
Klionsky DJ, Codogno P, Cuervo AM, Deretic V, Elazar Z, Fueyo-Margareto J, Gewirtz DA, Kroemer G, Levine B, Mizushima N, Rubinsztein DC, Thumm M, Tooze SA. Klionsky DJ, et al. Among authors: rubinsztein dc. Autophagy. 2010 May;6(4):438-48. doi: 10.4161/auto.6.4.12244. Epub 2010 May 16. Autophagy. 2010. PMID: 20484971 Free PMC article.
Rapamycin induces autophagic flux in neurons.
Rubinsztein DC, Nixon RA. Rubinsztein DC, et al. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):E181; author reply E182. doi: 10.1073/pnas.1014633107. Epub 2010 Nov 29. Proc Natl Acad Sci U S A. 2010. PMID: 21115811 Free PMC article. No abstract available.
Autophagy and aging.
Rubinsztein DC, Mariño G, Kroemer G. Rubinsztein DC, et al. Cell. 2011 Sep 2;146(5):682-95. doi: 10.1016/j.cell.2011.07.030. Cell. 2011. PMID: 21884931 Free article. Review.
A comprehensive glossary of autophagy-related molecules and processes (2nd edition).
Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, Levine B, Melia TJ, Mizushima N, Rubinsztein DC, Simonsen A, Thorburn A, Thumm M, Tooze SA. Klionsky DJ, et al. Among authors: rubinsztein dc. Autophagy. 2011 Nov;7(11):1273-94. doi: 10.4161/auto.7.11.17661. Epub 2011 Nov 1. Autophagy. 2011. PMID: 21997368 Free PMC article.
444 results