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Global analysis of protein structural changes in complex proteomes.
Feng Y, De Franceschi G, Kahraman A, Soste M, Melnik A, Boersema PJ, de Laureto PP, Nikolaev Y, Oliveira AP, Picotti P. Feng Y, et al. Among authors: boersema pj. Nat Biotechnol. 2014 Oct;32(10):1036-44. doi: 10.1038/nbt.2999. Epub 2014 Sep 14. Nat Biotechnol. 2014. PMID: 25218519
Proteomics beyond large-scale protein expression analysis.
Boersema PJ, Kahraman A, Picotti P. Boersema PJ, et al. Curr Opin Biotechnol. 2015 Aug;34:162-70. doi: 10.1016/j.copbio.2015.01.005. Epub 2015 Jan 28. Curr Opin Biotechnol. 2015. PMID: 25636126 Review.
Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dörig C, Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A, de Souza N, Picotti P. Cappelletti V, et al. Cell. 2021 Jan 21;184(2):545-559.e22. doi: 10.1016/j.cell.2020.12.021. Epub 2020 Dec 23. Cell. 2021. PMID: 33357446 Free PMC article.
Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity.
Soste M, Charmpi K, Lampert F, Gerez JA, van Oostrum M, Malinovska L, Boersema PJ, Prymaczok NC, Riek R, Peter M, Vanni S, Beyer A, Picotti P. Soste M, et al. Among authors: boersema pj. Cell Syst. 2019 Sep 25;9(3):309-320.e8. doi: 10.1016/j.cels.2019.07.010. Epub 2019 Sep 11. Cell Syst. 2019. PMID: 31521608 Free PMC article.
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates.
Laferrière F, Maniecka Z, Pérez-Berlanga M, Hruska-Plochan M, Gilhespy L, Hock EM, Wagner U, Afroz T, Boersema PJ, Barmettler G, Foti SC, Asi YT, Isaacs AM, Al-Amoudi A, Lewis A, Stahlberg H, Ravits J, De Giorgi F, Ichas F, Bezard E, Picotti P, Lashley T, Polymenidou M. Laferrière F, et al. Among authors: boersema pj. Nat Neurosci. 2019 Jan;22(1):65-77. doi: 10.1038/s41593-018-0294-y. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559480
36 results