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Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.
Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Essig K, et al. Nat Commun. 2018 Sep 19;9(1):3810. doi: 10.1038/s41467-018-06184-3. Nat Commun. 2018. PMID: 30232334 Free PMC article.
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.
Essig K, Hu D, Guimaraes JC, Alterauge D, Edelmann S, Raj T, Kranich J, Behrens G, Heiseke A, Floess S, Klein J, Maiser A, Marschall S, Hrabĕ de Angelis M, Leonhardt H, Calkhoven CF, Noessner E, Brocker T, Huehn J, Krug AB, Zavolan M, Baumjohann D, Heissmeyer V. Essig K, et al. Immunity. 2017 Dec 19;47(6):1067-1082.e12. doi: 10.1016/j.immuni.2017.11.008. Epub 2017 Dec 12. Immunity. 2017. PMID: 29246441 Free article.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
von Gamm M, Schaub A, Jones AN, Wolf C, Behrens G, Lichti J, Essig K, Macht A, Pircher J, Ehrlich A, Davari K, Chauhan D, Busch B, Wurst W, Feederle R, Feuchtinger A, Tschöp MH, Friedel CC, Hauck SM, Sattler M, Geerlof A, Hornung V, Heissmeyer V, Schulz C, Heikenwalder M, Glasmacher E. von Gamm M, et al. Among authors: essig k. J Exp Med. 2019 Jul 1;216(7):1700-1723. doi: 10.1084/jem.20181762. Epub 2019 May 24. J Exp Med. 2019. PMID: 31126966 Free PMC article.
24 results