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Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation.
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz JD, Andreasson KI. Minhas PS, et al. Among authors: contrepois k. Nat Immunol. 2019 Jan;20(1):50-63. doi: 10.1038/s41590-018-0255-3. Epub 2018 Nov 26. Nat Immunol. 2019. PMID: 30478397 Free PMC article.
Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice.
Chennamsetty I, Coronado M, Contrepois K, Keller MP, Carcamo-Orive I, Sandin J, Fajardo G, Whittle AJ, Fathzadeh M, Snyder M, Reaven G, Attie AD, Bernstein D, Quertermous T, Knowles JW. Chennamsetty I, et al. Among authors: contrepois k. Cell Rep. 2016 Oct 4;17(2):527-540. doi: 10.1016/j.celrep.2016.09.005. Cell Rep. 2016. PMID: 27705799 Free PMC article.
Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression.
Contrepois K, Coudereau C, Benayoun BA, Schuler N, Roux PF, Bischof O, Courbeyrette R, Carvalho C, Thuret JY, Ma Z, Derbois C, Nevers MC, Volland H, Redon CE, Bonner WM, Deleuze JF, Wiel C, Bernard D, Snyder MP, Rübe CE, Olaso R, Fenaille F, Mann C. Contrepois K, et al. Nat Commun. 2017 May 10;8:14995. doi: 10.1038/ncomms14995. Nat Commun. 2017. PMID: 28489069 Free PMC article.
A longitudinal big data approach for precision health.
Schüssler-Fiorenza Rose SM, Contrepois K, Moneghetti KJ, Zhou W, Mishra T, Mataraso S, Dagan-Rosenfeld O, Ganz AB, Dunn J, Hornburg D, Rego S, Perelman D, Ahadi S, Sailani MR, Zhou Y, Leopold SR, Chen J, Ashland M, Christle JW, Avina M, Limcaoco P, Ruiz C, Tan M, Butte AJ, Weinstock GM, Slavich GM, Sodergren E, McLaughlin TL, Haddad F, Snyder MP. Schüssler-Fiorenza Rose SM, et al. Among authors: contrepois k. Nat Med. 2019 May;25(5):792-804. doi: 10.1038/s41591-019-0414-6. Epub 2019 May 8. Nat Med. 2019. PMID: 31068711 Free PMC article.
Global metabolic profiling to model biological processes of aging in twins.
Bunning BJ, Contrepois K, Lee-McMullen B, Dhondalay GKR, Zhang W, Tupa D, Raeber O, Desai M, Nadeau KC, Snyder MP, Andorf S. Bunning BJ, et al. Among authors: contrepois k. Aging Cell. 2020 Jan;19(1):e13073. doi: 10.1111/acel.13073. Epub 2019 Nov 19. Aging Cell. 2020. PMID: 31746094 Free PMC article.
Personal aging markers and ageotypes revealed by deep longitudinal profiling.
Ahadi S, Zhou W, Schüssler-Fiorenza Rose SM, Sailani MR, Contrepois K, Avina M, Ashland M, Brunet A, Snyder M. Ahadi S, et al. Among authors: contrepois k. Nat Med. 2020 Jan;26(1):83-90. doi: 10.1038/s41591-019-0719-5. Epub 2020 Jan 13. Nat Med. 2020. PMID: 31932806 Free PMC article.
Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway.
Dubreuil MM, Morgens DW, Okumoto K, Honsho M, Contrepois K, Lee-McMullen B, Traber GM, Sood RS, Dixon SJ, Snyder MP, Fujiki Y, Bassik MC. Dubreuil MM, et al. Among authors: contrepois k. Cell Rep. 2020 Feb 4;30(5):1417-1433.e7. doi: 10.1016/j.celrep.2020.01.013. Cell Rep. 2020. PMID: 32023459 Free PMC article.
70 results