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High-throughput, quantitative analyses of genetic interactions in E. coli.
Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. Typas A, et al. Among authors: krogan nj. Nat Methods. 2008 Sep;5(9):781-7. doi: 10.1038/nmeth.1240. Nat Methods. 2008. PMID: 19160513 Free PMC article.
Global landscape of HIV-human protein complexes.
Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ. Jäger S, et al. Among authors: krogan nj. Nature. 2011 Dec 21;481(7381):365-70. doi: 10.1038/nature10719. Nature. 2011. PMID: 22190034 Free PMC article.
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.
Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ. Jäger S, et al. Among authors: krogan nj. Nature. 2011 Dec 21;481(7381):371-5. doi: 10.1038/nature10693. Nature. 2011. PMID: 22190037 Free PMC article.
Quantitative genetic-interaction mapping in mammalian cells.
Roguev A, Talbot D, Negri GL, Shales M, Cagney G, Bandyopadhyay S, Panning B, Krogan NJ. Roguev A, et al. Among authors: krogan nj. Nat Methods. 2013 May;10(5):432-7. doi: 10.1038/nmeth.2398. Epub 2013 Feb 13. Nat Methods. 2013. PMID: 23407553 Free PMC article.
Quantitative analysis of triple-mutant genetic interactions.
Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ. Braberg H, et al. Among authors: krogan nj. Nat Protoc. 2014 Aug;9(8):1867-81. doi: 10.1038/nprot.2014.127. Epub 2014 Jul 10. Nat Protoc. 2014. PMID: 25010907 Free PMC article.
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.
Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ. Kane JR, et al. Among authors: krogan nj. Cell Rep. 2015 May 26;11(8):1236-50. doi: 10.1016/j.celrep.2015.04.038. Epub 2015 May 14. Cell Rep. 2015. PMID: 25981045 Free PMC article.
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.
Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs D, Hamilton J, Leon PE, Chawdury A, Tripathi S, Melegari C, Campisi L, Hai R, Metreveli G, Gamarnik AV, García-Sastre A, Greenbaum B, Simon V, Fernandez-Sesma A, Krogan NJ, Mulder LCF, van Bakel H, Tortorella D, Taunton J, Palese P, Marazzi I. Heaton NS, et al. Among authors: krogan nj. Immunity. 2016 Jan 19;44(1):46-58. doi: 10.1016/j.immuni.2015.12.017. Immunity. 2016. PMID: 26789921 Free PMC article.
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. Mandegar MA, et al. Among authors: krogan nj. Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. Cell Stem Cell. 2016. PMID: 26971820 Free PMC article.
412 results