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Histone H4 lysine 16 acetylation regulates cellular lifespan.
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Dang W, et al. Nature. 2009 Jun 11;459(7248):802-7. doi: 10.1038/nature08085. Nature. 2009. PMID: 19516333 Free PMC article.
Identification and characterization of novel sirtuin inhibitor scaffolds.
Sanders BD, Jackson B, Brent M, Taylor AM, Dang W, Berger SL, Schreiber SL, Howitz K, Marmorstein R. Sanders BD, et al. Among authors: dang w. Bioorg Med Chem. 2009 Oct 1;17(19):7031-41. doi: 10.1016/j.bmc.2009.07.073. Epub 2009 Aug 3. Bioorg Med Chem. 2009. PMID: 19734050 Free PMC article.
MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, Thibault P, Verreault A, Johnson FB, Berger SL, Sternglanz R, McMahon SB, Côté J, Marmorstein R. Yuan H, et al. Among authors: dang w. EMBO J. 2012 Jan 4;31(1):58-70. doi: 10.1038/emboj.2011.382. Epub 2011 Oct 21. EMBO J. 2012. PMID: 22020126 Free PMC article.
Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL. Dang W, et al. Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814484 Free PMC article.
Development of organometallic S6K1 inhibitors.
Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Qin J, et al. Among authors: dang w. J Med Chem. 2015 Jan 8;58(1):305-14. doi: 10.1021/jm5011868. Epub 2014 Nov 13. J Med Chem. 2015. PMID: 25356520 Free PMC article.
552 results