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Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study.
Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. Rogers ZR, et al. Among authors: nalepa g. Haematologica. 2019 Oct;104(10):1974-1983. doi: 10.3324/haematol.2018.206540. Epub 2019 Apr 4. Haematologica. 2019. PMID: 30948484 Free PMC article. Clinical Trial.
L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry.
Vlachos A, Atsidaftos E, Lababidi ML, Muir E, Rogers ZR, Alhushki W, Bernstein J, Glader B, Gruner B, Hartung H, Knoll C, Loew T, Nalepa G, Narla A, Panigrahi AR, Sieff CA, Walkovich K, Farrar JE, Lipton JM. Vlachos A, et al. Among authors: nalepa g. Pediatr Blood Cancer. 2020 Dec;67(12):e28748. doi: 10.1002/pbc.28748. Epub 2020 Oct 6. Pediatr Blood Cancer. 2020. PMID: 33025707 Free PMC article. Clinical Trial.
Clinical features and outcomes of patients with Shwachman-Diamond syndrome and myelodysplastic syndrome or acute myeloid leukaemia: a multicentre, retrospective, cohort study.
Myers KC, Furutani E, Weller E, Siegele B, Galvin A, Arsenault V, Alter BP, Boulad F, Bueso-Ramos C, Burroughs L, Castillo P, Connelly J, Davies SM, DiNardo CD, Hanif I, Ho RH, Karras N, Manalang M, McReynolds LJ, Nakano TA, Nalepa G, Norkin M, Oberley MJ, Orgel E, Pastore YD, Rosenthal J, Walkovich K, Larson J, Malsch M, Elghetany MT, Fleming MD, Shimamura A. Myers KC, et al. Among authors: nalepa g. Lancet Haematol. 2020 Mar;7(3):e238-e246. doi: 10.1016/S2352-3026(19)30206-6. Epub 2019 Dec 23. Lancet Haematol. 2020. PMID: 31879230 Free PMC article.
An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
Zhou Y, He Y, Xing W, Zhang P, Shi H, Chen S, Shi J, Bai J, Rhodes SD, Zhang F, Yuan J, Yang X, Zhu X, Li Y, Hanenberg H, Xu M, Robertson KA, Yuan W, Nalepa G, Cheng T, Clapp DW, Yang FC. Zhou Y, et al. Among authors: nalepa g. Haematologica. 2017 Jun;102(6):1017-1027. doi: 10.3324/haematol.2016.158717. Epub 2017 Mar 24. Haematologica. 2017. PMID: 28341737 Free PMC article.
Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.
Pulliam-Leath AC, Ciccone SL, Nalepa G, Li X, Si Y, Miravalle L, Smith D, Yuan J, Li J, Anur P, Orazi A, Vance GH, Yang FC, Hanenberg H, Bagby GC, Clapp DW. Pulliam-Leath AC, et al. Among authors: nalepa g. Blood. 2010 Oct 21;116(16):2915-20. doi: 10.1182/blood-2009-08-240747. Epub 2010 Jul 6. Blood. 2010. PMID: 20606166 Free PMC article.
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia.
Edwards DM, Mitchell DK, Abdul-Sater Z, Chan KK, Sun Z, Sheth A, He Y, Jiang L, Yuan J, Sharma R, Czader M, Chin PJ, Liu Y, de Cárcer G, Nalepa G, Broxmeyer HE, Clapp DW, Sierra Potchanant EA. Edwards DM, et al. Among authors: nalepa g. Front Oncol. 2021 Nov 5;11:752933. doi: 10.3389/fonc.2021.752933. eCollection 2021. Front Oncol. 2021. PMID: 34804941 Free PMC article.
Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.
Staser K, Park SJ, Rhodes SD, Zeng Y, He YZ, Shew MA, Gehlhausen JR, Cerabona D, Menon K, Chen S, Sun Z, Yuan J, Ingram DA, Nalepa G, Yang FC, Clapp DW. Staser K, et al. Among authors: nalepa g. J Clin Invest. 2013 Jan;123(1):329-34. doi: 10.1172/JCI66167. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221339 Free PMC article.
47 results