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DNA damage detection in nucleosomes involves DNA register shifting.
Matsumoto S, Cavadini S, Bunker RD, Grand RS, Potenza A, Rabl J, Yamamoto J, Schenk AD, Schübeler D, Iwai S, Sugasawa K, Kurumizaka H, Thomä NH. Matsumoto S, et al. Among authors: thoma nh. Nature. 2019 Jul;571(7763):79-84. doi: 10.1038/s41586-019-1259-3. Epub 2019 May 29. Nature. 2019. PMID: 31142837 Free PMC article.
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
Scrima A, Konícková R, Czyzewski BK, Kawasaki Y, Jeffrey PD, Groisman R, Nakatani Y, Iwai S, Pavletich NP, Thomä NH. Scrima A, et al. Among authors: thoma nh. Cell. 2008 Dec 26;135(7):1213-23. doi: 10.1016/j.cell.2008.10.045. Cell. 2008. PMID: 19109893 Free PMC article.
Histone methylation by PRC2 is inhibited by active chromatin marks.
Schmitges FW, Prusty AB, Faty M, Stützer A, Lingaraju GM, Aiwazian J, Sack R, Hess D, Li L, Zhou S, Bunker RD, Wirth U, Bouwmeester T, Bauer A, Ly-Hartig N, Zhao K, Chan H, Gu J, Gut H, Fischle W, Müller J, Thomä NH. Schmitges FW, et al. Among authors: thoma nh. Mol Cell. 2011 May 6;42(3):330-41. doi: 10.1016/j.molcel.2011.03.025. Mol Cell. 2011. PMID: 21549310 Free article.
Determinants and dynamics of genome accessibility.
Bell O, Tiwari VK, Thomä NH, Schübeler D. Bell O, et al. Among authors: thoma nh. Nat Rev Genet. 2011 Jul 12;12(8):554-64. doi: 10.1038/nrg3017. Nat Rev Genet. 2011. PMID: 21747402 Review.
Crystal structure of the human COP9 signalosome.
Lingaraju GM, Bunker RD, Cavadini S, Hess D, Hassiepen U, Renatus M, Fischer ES, Thomä NH. Lingaraju GM, et al. Among authors: thoma nh. Nature. 2014 Aug 14;512(7513):161-5. doi: 10.1038/nature13566. Epub 2014 Jul 16. Nature. 2014. PMID: 25043011
77 results