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Antibody discovery and engineering by enhanced CRISPR-Cas9 integration of variable gene cassette libraries in mammalian cells.
MAbs. 2019 Nov-Dec;11(8):1367-1380. doi: 10.1080/19420862.2019.1662691. Epub 2019 Sep 16.
MAbs. 2019.
PMID: 31478465
Free PMC article.
Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells.
Neumeier D, Yermanos A, Agrafiotis A, Csepregi L, Chowdhury T, Ehling RA, Kuhn R, Cotet TS, Brisset-Di Roberto R, Di Tacchio M, Antonialli R, Starkie D, Lightwood DJ, Oxenius A, Reddy ST.
Neumeier D, et al. Among authors: di tacchio m.
Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2113766119. doi: 10.1073/pnas.2113766119. Epub 2022 Apr 29.
Proc Natl Acad Sci U S A. 2022.
PMID: 35486691
Free PMC article.
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A flow cytometry-based protocol for syngenic isolation of neurovascular unit cells from mouse and human tissues.
Spitzer D, Khel MI, Pütz T, Zinke J, Jia X, Sommer K, Filipski K, Thorsen F, Freiman TM, Günther S, Plate KH, Harter PN, Liebner S, Reiss Y, Di Tacchio M, Guérit S, Devraj K.
Spitzer D, et al. Among authors: di tacchio m.
Nat Protoc. 2023 May;18(5):1510-1542. doi: 10.1038/s41596-023-00805-y. Epub 2023 Mar 1.
Nat Protoc. 2023.
PMID: 36859615
Review.
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Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute ischemic stroke.
Spitzer D, Guérit S, Puetz T, Khel MI, Armbrust M, Dunst M, Macas J, Zinke J, Devraj G, Jia X, Croll F, Sommer K, Filipski K, Freiman TM, Looso M, Günther S, Di Tacchio M, Plate KH, Reiss Y, Liebner S, Harter PN, Devraj K.
Spitzer D, et al. Among authors: di tacchio m.
Acta Neuropathol. 2022 Aug;144(2):305-337. doi: 10.1007/s00401-022-02452-1. Epub 2022 Jun 25.
Acta Neuropathol. 2022.
PMID: 35752654
Free PMC article.
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Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF.
Di Tacchio M, Macas J, Weissenberger J, Sommer K, Bähr O, Steinbach JP, Senft C, Seifert V, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Scheel AH, Büttner R, Grauer OM, Schittenhelm J, Tabatabai G, Harter PN, Günther S, Devraj K, Plate KH, Reiss Y.
Di Tacchio M, et al.
Cancer Immunol Res. 2019 Dec;7(12):1910-1927. doi: 10.1158/2326-6066.CIR-18-0865. Epub 2019 Oct 9.
Cancer Immunol Res. 2019.
PMID: 31597643
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Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.
Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, Sommer K, Di Tacchio M, Vutukuri R, Beck H, Mittelbronn M, Foerch C, Pfeilschifter W, Liebner S, Peters KG, Plate KH, Reiss Y.
Gurnik S, et al. Among authors: di tacchio m.
Acta Neuropathol. 2016 May;131(5):753-73. doi: 10.1007/s00401-016-1551-3. Epub 2016 Mar 1.
Acta Neuropathol. 2016.
PMID: 26932603
Free PMC article.
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Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma.
Scholz A, Harter PN, Cremer S, Yalcin BH, Gurnik S, Yamaji M, Di Tacchio M, Sommer K, Baumgarten P, Bähr O, Steinbach JP, Trojan J, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Braun C, Schittenhelm J, Frueh JT, Ullrich E, Mittelbronn M, Plate KH, Reiss Y.
Scholz A, et al. Among authors: di tacchio m.
EMBO Mol Med. 2016 Jan 1;8(1):39-57. doi: 10.15252/emmm.201505505.
EMBO Mol Med. 2016.
PMID: 26666269
Free PMC article.
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Dendritic cell maturation in HCV infection: altered regulation of MHC class I antigen processing-presenting machinery.
Leone P, Di Tacchio M, Berardi S, Santantonio T, Fasano M, Ferrone S, Vacca A, Dammacco F, Racanelli V.
Leone P, et al. Among authors: di tacchio m.
J Hepatol. 2014 Aug;61(2):242-51. doi: 10.1016/j.jhep.2014.04.007. Epub 2014 Apr 13.
J Hepatol. 2014.
PMID: 24732300
Free PMC article.
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