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Membrane Disruption by Very Long Chain Fatty Acids during Necroptosis.
ACS Chem Biol. 2019 Oct 18;14(10):2286-2294. doi: 10.1021/acschembio.9b00616. Epub 2019 Sep 20.
ACS Chem Biol. 2019.
PMID: 31490656
Free PMC article.
Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis.
Pradhan AJ, Lu D, Parisi LR, Shen S, Berhane IA, Galster SL, Bynum K, Monje-Galvan V, Gokcumen O, Chemler SR, Qu J, Kay JG, Atilla-Gokcumen GE.
Pradhan AJ, et al. Among authors: galster sl.
Cell Chem Biol. 2021 Sep 16;28(9):1298-1309.e7. doi: 10.1016/j.chembiol.2021.03.012. Epub 2021 Apr 12.
Cell Chem Biol. 2021.
PMID: 33848465
Free PMC article.
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Enantioselective, Aerobic Copper-Catalyzed Intramolecular Carboamination and Carboetherification of Unactivated Alkenes.
Wdowik T, Galster SL, Carmo RLL, Chemler SR.
Wdowik T, et al. Among authors: galster sl.
ACS Catal. 2020 Aug 7;10(15):8535-8541. doi: 10.1021/acscatal.0c02607. Epub 2020 Jul 16.
ACS Catal. 2020.
PMID: 34306802
Free PMC article.
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Small-Molecule MMRi62 Induces Ferroptosis and Inhibits Metastasis in Pancreatic Cancer via Degradation of Ferritin Heavy Chain and Mutant p53.
Li J, Lama R, Galster SL, Inigo JR, Wu J, Chandra D, Chemler SR, Wang X.
Li J, et al. Among authors: galster sl.
Mol Cancer Ther. 2022 Apr 1;21(4):535-545. doi: 10.1158/1535-7163.MCT-21-0728.
Mol Cancer Ther. 2022.
PMID: 35131878
Free PMC article.
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Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status.
Lama R, Xu C, Galster SL, Querol-García J, Portwood S, Mavis CK, Ruiz FM, Martin D, Wu J, Giorgi MC, Bargonetti J, Wang ES, Hernandez-Ilizaliturri FJ, Koudelka GB, Chemler SR, Muñoz IG, Wang X.
Lama R, et al. Among authors: galster sl.
Front Oncol. 2022 Aug 5;12:933446. doi: 10.3389/fonc.2022.933446. eCollection 2022.
Front Oncol. 2022.
PMID: 35992795
Free PMC article.
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Dual Targeting of MDM4 and FTH1 by MMRi71 for Induced Protein Degradation and p53-Independent Apoptosis in Leukemia Cells.
Lama R, Galster SL, Xu C, Davison LW, Chemler SR, Wang X.
Lama R, et al. Among authors: galster sl.
Molecules. 2022 Nov 8;27(22):7665. doi: 10.3390/molecules27227665.
Molecules. 2022.
PMID: 36431769
Free PMC article.
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Copper-Catalyzed Enantioselective Aerobic Alkene Aminooxygenation and Dioxygenation: Access to 2-Formyl Saturated Heterocycles and Unnatural Proline Derivatives.
Carmo RLL, Galster SL, Wdowik T, Song C, Chemler SR.
Carmo RLL, et al. Among authors: galster sl.
J Am Chem Soc. 2023 Jun 28;145(25):13715-13729. doi: 10.1021/jacs.3c01985. Epub 2023 Jun 16.
J Am Chem Soc. 2023.
PMID: 37327484
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