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KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.
Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB. Lear TB, et al. JCI Insight. 2019 Oct 3;4(19):e129110. doi: 10.1172/jci.insight.129110. JCI Insight. 2019. PMID: 31578312 Free PMC article.
E3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumonia.
Chen BB, Coon TA, Glasser JR, Zou C, Ellis B, Das T, McKelvey AC, Rajbhandari S, Lear T, Kamga C, Shiva S, Li C, Pilewski JM, Callio J, Chu CT, Ray A, Ray P, Tyurina YY, Kagan VE, Mallampalli RK. Chen BB, et al. Cell Rep. 2014 Apr 24;7(2):476-487. doi: 10.1016/j.celrep.2014.02.048. Epub 2014 Apr 3. Cell Rep. 2014. PMID: 24703837 Free PMC article.
Novel PDE4 inhibitors derived from Chinese medicine forsythia.
Coon TA, McKelvey AC, Weathington NM, Birru RL, Lear T, Leikauf GD, Chen BB. Coon TA, et al. PLoS One. 2014 Dec 30;9(12):e115937. doi: 10.1371/journal.pone.0115937. eCollection 2014. PLoS One. 2014. PMID: 25549252 Free PMC article.
Therapeutic targets in fibrotic pathways.
Lear T, Chen BB. Lear T, et al. Cytokine. 2016 Dec;88:193-195. doi: 10.1016/j.cyto.2016.09.008. Epub 2016 Sep 19. Cytokine. 2016. PMID: 27658114 Free PMC article.
31 results