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KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.
Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB. Lear TB, et al. Among authors: shlomchik mj. JCI Insight. 2019 Oct 3;4(19):e129110. doi: 10.1172/jci.insight.129110. JCI Insight. 2019. PMID: 31578312 Free PMC article.
Lupus and proliferative nephritis are PAD4 independent in murine models.
Gordon RA, Herter JM, Rosetti F, Campbell AM, Nishi H, Kashgarian M, Bastacky SI, Marinov A, Nickerson KM, Mayadas TN, Shlomchik MJ. Gordon RA, et al. Among authors: shlomchik mj. JCI Insight. 2017 May 18;2(10):e92926. doi: 10.1172/jci.insight.92926. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515361 Free PMC article.
Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
Weisel FJ, Mullett SJ, Elsner RA, Menk AV, Trivedi N, Luo W, Wikenheiser D, Hawse WF, Chikina M, Smita S, Conter LJ, Joachim SM, Wendell SG, Jurczak MJ, Winkler TH, Delgoffe GM, Shlomchik MJ. Weisel FJ, et al. Among authors: shlomchik mj. Nat Immunol. 2020 Mar;21(3):331-342. doi: 10.1038/s41590-020-0598-4. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066950 Free PMC article.
B cell-intrinsic TLR9 expression is protective in murine lupus.
Tilstra JS, John S, Gordon RA, Leibler C, Kashgarian M, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: shlomchik mj. J Clin Invest. 2020 Jun 1;130(6):3172-3187. doi: 10.1172/JCI132328. J Clin Invest. 2020. PMID: 32191633 Free PMC article.
Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model.
Gordon RA, Tilstra JS, Marinov A, Nickerson KM, Bastacky SI, Shlomchik MJ. Gordon RA, et al. Among authors: shlomchik mj. PLoS One. 2020 Apr 3;15(4):e0226396. doi: 10.1371/journal.pone.0226396. eCollection 2020. PLoS One. 2020. PMID: 32243431 Free PMC article.
Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.
Leibler C, John S, Elsner RA, Thomas KB, Smita S, Joachim S, Levack RC, Callahan DJ, Gordon RA, Bastacky S, Fukui R, Miyake K, Gingras S, Nickerson KM, Shlomchik MJ. Leibler C, et al. Among authors: shlomchik mj. Nat Immunol. 2022 Oct;23(10):1457-1469. doi: 10.1038/s41590-022-01310-2. Epub 2022 Sep 23. Nat Immunol. 2022. PMID: 36151396 Free PMC article.
B cell-intrinsic Myd88 regulates disease progression in murine lupus.
Tilstra JS, Kim M, Gordon RA, Leibler C, Cosgrove HA, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: shlomchik mj. J Exp Med. 2023 Dec 4;220(12):e20230263. doi: 10.1084/jem.20230263. Epub 2023 Oct 3. J Exp Med. 2023. PMID: 37787782 Free PMC article.
B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex.
Wallace CH, Wu BX, Salem M, Ansa-Addo EA, Metelli A, Sun S, Gilkeson G, Shlomchik MJ, Liu B, Li Z. Wallace CH, et al. Among authors: shlomchik mj. JCI Insight. 2018 Apr 5;3(7):e99863. doi: 10.1172/jci.insight.99863. eCollection 2018 Apr 5. JCI Insight. 2018. PMID: 29618665 Free PMC article.
217 results