Brown AL - Search Results

1

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.

Kim J, Gupta R, Blanco LP, Yang S, Shteinfer-Kuzmine A, Wang K, Zhu J, Yoon HE, Wang X, Kerkhofs M, Kang H, Brown AL, Park SJ, Xu X, Zandee van Rilland E, Kim MK, Cohen JI, Kaplan MJ, Shoshan-Barmatz V, Chung JH. Kim J, et al. Among authors: brown al. Science. 2019 Dec 20;366(6472):1531-1536. doi: 10.1126/science.aav4011. Epub 2019 Dec 19. Science. 2019. PMID: 31857488 Free PMC article.

2

Brown AL, Lee CH, Schwarz JK, Mitiku N, Piwnica-Worms H, Chung JH. Brown AL, et al. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3745-50. doi: 10.1073/pnas.96.7.3745. Proc Natl Acad Sci U S A. 1999. PMID: 10097108 Free PMC article.

3

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response.

Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. Lee JS, et al. Among authors: brown al. Nature. 2000 Mar 9;404(6774):201-4. doi: 10.1038/35004614. Nature. 2000. PMID: 10724175

4

The function of BRCA1 in DNA damage response.

Lee JS, Collins K, Brown A, Lee CH, Chung JH. Lee JS, et al. Cold Spring Harb Symp Quant Biol. 2000;65:547-52. doi: 10.1101/sqb.2000.65.547. Cold Spring Harb Symp Quant Biol. 2000. PMID: 12760072 Review. No abstract available.

5

Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation.

Yang S, Jeong JH, Brown AL, Lee CH, Pandolfi PP, Chung JH, Kim MK. Yang S, et al. Among authors: brown al. J Biol Chem. 2006 Sep 8;281(36):26645-54. doi: 10.1074/jbc.M604391200. Epub 2006 Jul 11. J Biol Chem. 2006. PMID: 16835227 Free article.

6

Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage.

Kang SG, Brown AL, Chung JH. Kang SG, et al. Among authors: brown al. J Biol Chem. 2007 Mar 2;282(9):6090-7. doi: 10.1074/jbc.M610659200. Epub 2006 Dec 19. J Biol Chem. 2007. PMID: 17179152 Free article.

7

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.

Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V, Chung JH. Park SJ, et al. Among authors: brown al. Cell. 2012 Feb 3;148(3):421-33. doi: 10.1016/j.cell.2012.01.017. Cell. 2012. PMID: 22304913 Free PMC article.

8

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.

Um JH, Brown AL, Singh SK, Chen Y, Gucek M, Lee BS, Luckey MA, Kim MK, Park JH, Sleckman BP, Gellert M, Chung JH. Um JH, et al. Among authors: brown al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9873-8. doi: 10.1073/pnas.1307928110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716691 Free PMC article.

9

Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.

Mishra A, Brown AL, Yao X, Yang S, Park SJ, Liu C, Dagur PK, McCoy JP, Keeran KJ, Nugent GZ, Jeffries KR, Qu X, Yu ZX, Levine SJ, Chung JH. Mishra A, et al. Among authors: brown al. Nat Commun. 2015 Feb 18;6:6224. doi: 10.1038/ncomms7224. Nat Commun. 2015. PMID: 25692509 Free PMC article.

10

Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.

Park SJ, Ahmad F, Um JH, Brown AL, Xu X, Kang H, Ke H, Feng X, Ryall J, Philp A, Schenk S, Kim MK, Sartorelli V, Chung JH. Park SJ, et al. Among authors: brown al. EBioMedicine. 2017 Apr;18:128-138. doi: 10.1016/j.ebiom.2017.03.019. Epub 2017 Mar 14. EBioMedicine. 2017. PMID: 28396013 Free PMC article.

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