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Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis.
Flores AM, Hosseini-Nassab N, Jarr KU, Ye J, Zhu X, Wirka R, Koh AL, Tsantilas P, Wang Y, Nanda V, Kojima Y, Zeng Y, Lotfi M, Sinclair R, Weissman IL, Ingelsson E, Smith BR, Leeper NJ. Flores AM, et al. Among authors: wirka r. Nat Nanotechnol. 2020 Feb;15(2):154-161. doi: 10.1038/s41565-019-0619-3. Epub 2020 Jan 27. Nat Nanotechnol. 2020. PMID: 31988506 Free PMC article.
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Wirka RC, et al. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. Nat Med. 2019. PMID: 31359001 Free PMC article.
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Tashima Y, Shad R, Cheng P, Wirka R, Churovich S, Nakamura K, Yokoyama N, Cui JZ, Iosef C, Hiesinger W, Quertermous T, Fischbein MP. Pedroza AJ, et al. Among authors: wirka r. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2195-2211. doi: 10.1161/ATVBAHA.120.314670. Epub 2020 Jul 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32698686 Free PMC article.
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis.
Cheng P, Wirka RC, Shoa Clarke L, Zhao Q, Kundu R, Nguyen T, Nair S, Sharma D, Kim HJ, Shi H, Assimes T, Brian Kim J, Kundaje A, Quertermous T. Cheng P, et al. Among authors: wirka rc. Circulation. 2022 Feb 8;145(6):469-485. doi: 10.1161/CIRCULATIONAHA.121.057789. Epub 2022 Jan 6. Circulation. 2022. PMID: 34990206 Free PMC article.
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.
Röhl S, Rykaczewska U, Seime T, Suur BE, Diez MG, Gådin JR, Gainullina A, Sergushichev AA, Wirka R, Lengquist M, Kronqvist M, Bergman O, Odeberg J, Lindeman JHN, Quertermous T, Hamsten A, Eriksson P, Hedin U, Razuvaev A, Matic LP. Röhl S, et al. Among authors: wirka r. JVS Vasc Sci. 2020 Feb 7;1:13-27. doi: 10.1016/j.jvssci.2020.01.001. eCollection 2020. JVS Vasc Sci. 2020. PMID: 34617037 Free PMC article.
29 results