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Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells.
Kim EY, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio A, Tamura T, Leaf DE, Baron RM, Shay T, Brenner MB. Kim EY, et al. Among authors: arciniegas rubio a. J Clin Invest. 2020 Jun 1;130(6):3238-3252. doi: 10.1172/JCI128075. J Clin Invest. 2020. PMID: 32154791 Free PMC article.
mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury.
Lee H, Fei Q, Streicher A, Zhang W, Isabelle C, Patel P, Lam HC, Arciniegas-Rubio A, Pinilla-Vera M, Amador-Munoz DP, Barragan-Bradford D, Higuera-Moreno A, Putman RK, Sholl LM, Henske EP, Bobba CM, Higuita-Castro N, Shalosky EM, Hite RD, Christman JW, Ghadiali SN, Baron RM, Englert JA. Lee H, et al. Among authors: arciniegas rubio a. JCI Insight. 2021 Jul 22;6(14):e137708. doi: 10.1172/jci.insight.137708. JCI Insight. 2021. PMID: 34138757 Free PMC article.
Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut.
Varon J, Arciniegas Rubio A, Amador-Munoz D, Corcoran A, DeCorte JA, Isabelle C, Pinilla Vera M, Walker K, Brown L, Cernadas M, Bry L, Yang H, Kitsios GD, McVerry BJ, Morris A, Lee H, Howrylak J, Englert JA, Baron RM. Varon J, et al. Among authors: arciniegas rubio a. Crit Care Explor. 2022 May 18;4(5):e0699. doi: 10.1097/CCE.0000000000000699. eCollection 2022 May. Crit Care Explor. 2022. PMID: 35620769 Free PMC article.
The upper and lower respiratory tract microbiome in severe aspiration pneumonia.
Kitsios GD, Nguyen VD, Sayed K, Al-Yousif N, Schaefer C, Shah FA, Bain W, Yang H, Fitch A, Li K, Wang X, Qin S, Gentry H, Zhang Y, Varon J, Arciniegas Rubio A, Englert JA, Baron RM, Lee JS, Methé B, Benos PV, Morris A, McVerry BJ. Kitsios GD, et al. Among authors: arciniegas rubio a. iScience. 2023 May 6;26(6):106832. doi: 10.1016/j.isci.2023.106832. eCollection 2023 Jun 16. iScience. 2023. PMID: 37250794 Free PMC article.