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Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells.
Kim EY, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio A, Tamura T, Leaf DE, Baron RM, Shay T, Brenner MB. Kim EY, et al. Among authors: choi j. J Clin Invest. 2020 Jun 1;130(6):3238-3252. doi: 10.1172/JCI128075. J Clin Invest. 2020. PMID: 32154791 Free PMC article.
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.
Wang Y, Mohseni M, Grauel A, Diez JE, Guan W, Liang S, Choi JE, Pu M, Chen D, Laszewski T, Schwartz S, Gu J, Mansur L, Burks T, Brodeur L, Velazquez R, Kovats S, Pant B, Buruzula G, Deng E, Chen JT, Sari-Sarraf F, Dornelas C, Varadarajan M, Yu H, Liu C, Lim J, Hao HX, Jiang X, Malamas A, LaMarche MJ, Geyer FC, McLaughlin M, Costa C, Wagner J, Ruddy D, Jayaraman P, Kirkpatrick ND, Zhang P, Iartchouk O, Aardalen K, Cremasco V, Dranoff G, Engelman JA, Silver S, Wang H, Hastings WD, Goldoni S. Wang Y, et al. Among authors: choi je. Sci Rep. 2021 Jan 14;11(1):1399. doi: 10.1038/s41598-021-80999-x. Sci Rep. 2021. PMID: 33446805 Free PMC article.
Targeting PKM2 signaling cascade with salvianic acid A normalizes tumor blood vessels to facilitate chemotherapeutic drug delivery.
Qian C, Zhou Y, Zhang T, Dong G, Song M, Tang Y, Wei Z, Yu S, Shen Q, Chen W, Choi JP, Yan J, Zhong C, Wan L, Li J, Wang A, Lu Y, Zhao Y. Qian C, et al. Among authors: choi jp. Acta Pharm Sin B. 2024 May;14(5):2077-2096. doi: 10.1016/j.apsb.2024.02.003. Epub 2024 Feb 23. Acta Pharm Sin B. 2024. PMID: 38799619 Free PMC article.
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