Hu X - Search Results

1

Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1.

Hu Z, Rolt A, Hu X, Ma CD, Le DJ, Park SB, Houghton M, Southall N, Anderson DE, Talley DC, Lloyd JR, Marugan JC, Liang TJ. Hu Z, et al. Among authors: hu x. Cell Chem Biol. 2020 Jul 16;27(7):780-792.e5. doi: 10.1016/j.chembiol.2020.04.006. Epub 2020 May 7. Cell Chem Biol. 2020. PMID: 32386595 Free PMC article.

2

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.

He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang AQ, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer M, Zheng W, Chayama K, Marugan JJ, Liang TJ. He S, et al. Among authors: hu x, hu z. Sci Transl Med. 2015 Apr 8;7(282):282ra49. doi: 10.1126/scitranslmed.3010286. Sci Transl Med. 2015. PMID: 25855495 Free PMC article.

3

Identification of novel anti-hepatitis C virus agents by a quantitative high throughput screen in a cell-based infection assay.

Hu Z, Hu X, He S, Yim HJ, Xiao J, Swaroop M, Tanega C, Zhang YQ, Yi G, Kao CC, Marugan J, Ferrer M, Zheng W, Southall N, Liang TJ. Hu Z, et al. Among authors: hu x. Antiviral Res. 2015 Dec;124:20-9. doi: 10.1016/j.antiviral.2015.10.018. Epub 2015 Oct 26. Antiviral Res. 2015. PMID: 26515788 Free PMC article.

4

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.

He S, Xiao J, Dulcey AE, Lin B, Rolt A, Hu Z, Hu X, Wang AQ, Xu X, Southall N, Ferrer M, Zheng W, Liang TJ, Marugan JJ. He S, et al. Among authors: hu x, hu z. J Med Chem. 2016 Feb 11;59(3):841-53. doi: 10.1021/acs.jmedchem.5b00752. Epub 2016 Feb 1. J Med Chem. 2016. PMID: 26599718 Free PMC article.

5

Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle.

He S, Li K, Lin B, Hu Z, Xiao J, Hu X, Wang AQ, Xu X, Ferrer M, Southall N, Zheng W, Aubé J, Schoenen FJ, Marugan JJ, Liang TJ, Frankowski KJ. He S, et al. Among authors: hu x, hu z. J Med Chem. 2017 Jul 27;60(14):6364-6383. doi: 10.1021/acs.jmedchem.7b00561. Epub 2017 Jul 13. J Med Chem. 2017. PMID: 28636348 Free PMC article.

6

Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion.

Ma CD, Imamura M, Talley DC, Rolt A, Xu X, Wang AQ, Le D, Uchida T, Osawa M, Teraoka Y, Li K, Hu X, Park SB, Chalasani N, Irvin PH, Dulcey AE, Southall N, Marugan JJ, Hu Z, Chayama K, Frankowski KJ, Liang TJ. Ma CD, et al. Among authors: hu x, hu z. Nat Microbiol. 2020 Dec;5(12):1532-1541. doi: 10.1038/s41564-020-0781-2. Epub 2020 Aug 31. Nat Microbiol. 2020. PMID: 32868923 Free PMC article.

7

Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compounds.

Hu Z, Lan KH, He S, Swaroop M, Hu X, Southall N, Zheng W, Liang TJ. Hu Z, et al. Among authors: hu x. Antimicrob Agents Chemother. 2014;58(2):995-1004. doi: 10.1128/AAC.02094-13. Epub 2013 Nov 25. Antimicrob Agents Chemother. 2014. PMID: 24277038 Free PMC article.

8

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.

He S, Jain P, Lin B, Ferrer M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan JJ, Liang TJ, Frankowski KJ. He S, et al. Among authors: hu x, hu z. ACS Comb Sci. 2015 Oct 12;17(10):641-52. doi: 10.1021/acscombsci.5b00101. Epub 2015 Sep 17. ACS Comb Sci. 2015. PMID: 26332742 Free PMC article.

9

Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions.

Chiang N, Barnaeva E, Hu X, Marugan J, Southall N, Ferrer M, Serhan CN. Chiang N, et al. Among authors: hu x. Cell Chem Biol. 2019 Feb 21;26(2):244-254.e4. doi: 10.1016/j.chembiol.2018.10.023. Epub 2018 Dec 13. Cell Chem Biol. 2019. PMID: 30554914 Free PMC article.

10

Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding.

Huang BX, Hu X, Kwon HS, Fu C, Lee JW, Southall N, Marugan J, Kim HY. Huang BX, et al. Among authors: hu x. Commun Biol. 2020 Mar 6;3(1):109. doi: 10.1038/s42003-020-0831-6. Commun Biol. 2020. PMID: 32144388 Free PMC article.

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