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Timing matters: real-world effectiveness of early combination of biologic and conventional synthetic disease-modifying antirheumatic drugs for treating newly diagnosed polyarticular course juvenile idiopathic arthritis.
Huang B, Qiu T, Chen C, Zhang Y, Seid M, Lovell D, Brunner HI, Morgan EM; Patient Centered Adaptive Treatment Strategies (PCATS). Huang B, et al. Among authors: chen c. RMD Open. 2020 Jan;6(1):e001091. doi: 10.1136/rmdopen-2019-001091. RMD Open. 2020. PMID: 32396520 Free PMC article.
Risk, Timing, and Predictors of Disease Flare After Discontinuation of Anti-Tumor Necrosis Factor Therapy in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis With Clinically Inactive Disease.
Lovell DJ, Johnson AL, Huang B, Gottlieb BS, Morris PW, Kimura Y, Onel K, Li SC, Grom AA, Taylor J, Brunner HI, Huggins JL, Nocton JJ, Haines KA, Edelheit BS, Shishov M, Jung LK, Williams CB, Tesher MS, Costanzo DM, Zemel LS, Dare JA, Passo MH, Ede KC, Olson JC, Cassidy EA, Griffin TA, Wagner-Weiner L, Weiss JE, Vogler LB, Rouster-Stevens KA, Beukelman T, Cron RQ, Kietz D, Schikler K, Schmidt KM, Mehta J, Wahezi DM, Ting TV, Verbsky JW, Eberhard BA, Spalding S, Chen C, Giannini EH. Lovell DJ, et al. Among authors: chen c. Arthritis Rheumatol. 2018 Sep;70(9):1508-1518. doi: 10.1002/art.40509. Epub 2018 Jul 25. Arthritis Rheumatol. 2018. PMID: 29604189 Free PMC article.
Immunome perturbation is present in patients with juvenile idiopathic arthritis who are in remission and will relapse upon anti-TNFα withdrawal.
Leong JY, Chen P, Yeo JG, Ally F, Chua C, Nur Hazirah S, Poh SL, Pan L, Lai L, Lee ESC, Bathi LDT, Arkachaisri T, Lovell D, Albani S; Pediatric Rheumatology Collaborative Study Group. Leong JY, et al. Among authors: chen p. Ann Rheum Dis. 2019 Dec;78(12):1712-1721. doi: 10.1136/annrheumdis-2019-216059. Epub 2019 Sep 20. Ann Rheum Dis. 2019. PMID: 31540934 Free PMC article.
Functional Ability and Health-Related Quality of Life in Randomized Controlled Trials of Tocilizumab in Patients With Juvenile Idiopathic Arthritis.
Brunner HI, Chen C, Bovis F, De Benedetti F, Espada G, Joos R, Akikusa J, Chaitow J, Boteanu AL, Kimura Y, Rietschel C, Siri D, Smolewska E, Schmeling H, Brown DE, Martini A, Lovell DJ, Huang B, Ruperto N; Paediatric Rheumatology International Trials Organisation and the Pediatric Rheumatology Collaborative Study Group. Brunner HI, et al. Among authors: chen c. Arthritis Care Res (Hoboken). 2021 Sep;73(9):1264-1274. doi: 10.1002/acr.24384. Epub 2021 Aug 2. Arthritis Care Res (Hoboken). 2021. PMID: 32702212
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