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Valvular interstitial cells suppress calcification of valvular endothelial cells.
Hjortnaes J, Shapero K, Goettsch C, Hutcheson JD, Keegan J, Kluin J, Mayer JE, Bischoff J, Aikawa E. Hjortnaes J, et al. Among authors: aikawa e. Atherosclerosis. 2015 Sep;242(1):251-260. doi: 10.1016/j.atherosclerosis.2015.07.008. Epub 2015 Jul 17. Atherosclerosis. 2015. PMID: 26232165 Free PMC article.
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
Goettsch C, Hutcheson JD, Hagita S, Rogers MA, Creager MD, Pham T, Choi J, Mlynarchik AK, Pieper B, Kjolby M, Aikawa M, Aikawa E. Goettsch C, et al. Among authors: aikawa m, aikawa e. Atherosclerosis. 2016 Aug;251:109-118. doi: 10.1016/j.atherosclerosis.2016.06.011. Epub 2016 Jun 9. Atherosclerosis. 2016. PMID: 27318830 Free PMC article.
Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis.
Zheng KH, Tsimikas S, Pawade T, Kroon J, Jenkins WSA, Doris MK, White AC, Timmers NKLM, Hjortnaes J, Rogers MA, Aikawa E, Arsenault BJ, Witztum JL, Newby DE, Koschinsky ML, Fayad ZA, Stroes ESG, Boekholdt SM, Dweck MR. Zheng KH, et al. Among authors: aikawa e. J Am Coll Cardiol. 2019 May 7;73(17):2150-2162. doi: 10.1016/j.jacc.2019.01.070. J Am Coll Cardiol. 2019. PMID: 31047003 Free PMC article.
Innate and adaptive immunity in cardiovascular calcification.
Passos LSA, Lupieri A, Becker-Greene D, Aikawa E. Passos LSA, et al. Among authors: aikawa e. Atherosclerosis. 2020 Aug;306:59-67. doi: 10.1016/j.atherosclerosis.2020.02.016. Epub 2020 Feb 28. Atherosclerosis. 2020. PMID: 32222287 Free PMC article. Review.
ApoC-III is a novel inducer of calcification in human aortic valves.
Schlotter F, de Freitas RCC, Rogers MA, Blaser MC, Wu PJ, Higashi H, Halu A, Iqbal F, Andraski AB, Rodia CN, Kuraoka S, Wen JR, Creager M, Pham T, Hutcheson JD, Body SC, Kohan AB, Sacks FM, Aikawa M, Singh SA, Aikawa E. Schlotter F, et al. Among authors: aikawa m, aikawa e. J Biol Chem. 2021 Jan-Jun;296:100193. doi: 10.1074/jbc.RA120.015700. Epub 2021 Jan 6. J Biol Chem. 2021. PMID: 33334888 Free PMC article.
318 results