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Restoring metabolism of myeloid cells reverses cognitive decline in ageing.
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, Joshi AU, He JQ, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon PK, Majeti R, Suematsu M, Mochly-Rosen D, Weissman IL, Longo FM, Rabinowitz JD, Andreasson KI. Minhas PS, et al. Among authors: latif hernandez a. Nature. 2021 Feb;590(7844):122-128. doi: 10.1038/s41586-020-03160-0. Epub 2021 Jan 20. Nature. 2021. PMID: 33473210 Free PMC article.
The two faces of synaptic failure in AppNL-G-F knock-in mice.
Latif-Hernandez A, Sabanov V, Ahmed T, Craessaerts K, Saito T, Saido T, Balschun D. Latif-Hernandez A, et al. Alzheimers Res Ther. 2020 Aug 24;12(1):100. doi: 10.1186/s13195-020-00667-6. Alzheimers Res Ther. 2020. PMID: 32838792 Free PMC article.
Early pathologic amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition.
Shah D, Praet J, Latif Hernandez A, Höfling C, Anckaerts C, Bard F, Morawski M, Detrez JR, Prinsen E, Villa A, De Vos WH, Maggi A, D'Hooge R, Balschun D, Rossner S, Verhoye M, Van der Linden A. Shah D, et al. Among authors: latif hernandez a. Alzheimers Dement. 2016 Sep;12(9):964-976. doi: 10.1016/j.jalz.2016.03.010. Epub 2016 Apr 21. Alzheimers Dement. 2016. PMID: 27107518
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.
Latif-Hernandez A, Yang T, Raymond-Butler R 3rd, Losada PM, Minhas PS, White H, Tran KC, Liu H, Simmons DA, Langness V, Andreasson KI, Wyss-Coray T, Longo FM. Latif-Hernandez A, et al. Alzheimers Dement. 2024 May 23. doi: 10.1002/alz.13857. Online ahead of print. Alzheimers Dement. 2024. PMID: 38779814
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.
Latif-Hernandez A, Yang T, Raymond-Butler R, Losada PM, Minhas P, White H, Tran KC, Liu H, Simmons DA, Langness V, Andreasson K, Wyss-Coray T, Longo FM. Latif-Hernandez A, et al. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558138. doi: 10.1101/2023.09.18.558138. bioRxiv. 2023. PMID: 37781573 Free PMC article. Preprint.